六亚甲基-双-[二甲基-(3-邻苯二甲酰亚氨基丙基)氨基]二溴化物合成路线 （共 4 条）
反应条件
in acetonitrile 0.35 h; Microwave irradiation;
参考文献
Heller, Eberhard; Lautenschlaeger, Werner; Holzgrabe, Ulrike
Tetrahedron Letters, 2009 , vol. 50, # 12 p. 1321 - 1323
反应条件
1: 91 percent / p-TsOH / toluene / 0.5 h / 115 °C / microwave irradiation 2: 97 percent / KI; K2CO3 / 2 h / 100 °C / microwave irradiation View Scheme
参考文献
Schmitz, Jens; Heller, Eberhard; Holzgrabe, Ulrike
Monatshefte fur Chemie, 2007 , vol. 138, # 2 p. 171 - 174
反应条件
1: 91 percent / p-TsOH / toluene / 0.5 h / 115 °C / microwave irradiation 2: 97 percent / KI; K2CO3 / 2 h / 100 °C / microwave irradiation View Scheme
参考文献
Schmitz, Jens; Heller, Eberhard; Holzgrabe, Ulrike
Monatshefte fur Chemie, 2007 , vol. 138, # 2 p. 171 - 174
反应条件
water
MgHPO4, Tris, pH 7.4; stability (half-life time ca. 5 h);
参考文献
Holzgrabe, Ulrike; Mohr, K.; Pfeffer, J.
Archiv der Pharmazie (Weinheim, Germany), 1990 , vol. 323, # 9 p. 651
