2-氨基-3-碘-5-甲基吡啶合成路线 （共 3 条）
反应条件
N-iodo-succinimide; trifluorormethanesulfonic acid 0.25 h; Heating / reflux;
参考文献
ASTRAZENECA AB
Patent: WO2004/16609 A1, 2004 ;
Location in patent: Page 47 ;
WO 2004/016609 A1
反应条件
1,4-diaza-bicyclo[2.2.2]octane; bis-triphenylphosphine-palladium(II) chloride in N,N-dimethyl-formamide T=110°C; 16 h;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2008/4117 A1, 2008 ;
Location in patent: Page/Page column 106-107 ;
反应条件
in ethanol; water
24 h; Heating;
参考文献
Veron, Jean-Baptiste; Allouchi, Hassan; Enguehard-Gueiffier, Cecile; Snoeck, Robert; Andrei, Graciela; De Clercq, Erik; Gueiffier, Alain
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 21 p. 9536 - 9545
