1.1: lithium aluminium tetrahydride / tetrahydrofuran; diethyl ether / 2 h / 0 °C / Inert atmosphere 2.1: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere 3.1: water; acetic acid / 2 h / 20 - 50 °C 4.1: 1H-imidazole; 4-(N,N-dimethlyamino)pyridine / dichloromethane / 0 - 20 °C / Inert atmosphere 5.1: pyridine; hydrogen fluoride / tetrahydrofuran / 7 h / 0 - 20 °C / Inert atmosphere 6.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 1 h / -78 °C / Inert atmosphere 6.2: -78 - 20 °C / Inert atmosphere 7.1: tert.-butyl lithium / diethyl ether; pentane / 0.08 h / -78 °C / Inert atmosphere 7.2: 0.67 h / 0 °C / Inert atmosphere 7.3: 3.5 h / 0 - 20 °C / Inert atmosphere 8.1: 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; [bis(acetoxy)iodo]benzene / dichloromethane / 20 °C / Inert atmosphere 9.1: n-butyllithium; chloro-trimethyl-silane; triethylamine; diisopropylamine / tetrahydrofuran; hexanes / -78 - 20 °C / Inert atmosphere 9.2: 120 °C / Inert atmosphere 10.1: methanol; diethyl ether; benzene / 1.5 h / 6 - 20 °C / Inert atmosphere 11.1: pyridine; hydrogen fluoride / tetrahydrofuran / 24 h / 0 - 20 °C / Inert atmosphere 12.1: pyridinium chlorochromate / dichloromethane / 2.5 h / 0 - 20 °C / Inert atmosphere; Celite 13.1: toluene / 110 °C / Inert atmosphere; Molecular sieve; Sealed tube 13.2: 5.58 h / 0 - 20 °C / Molecular sieve 14.1: PHT / tetrahydrofuran / 72 h / 20 °C / Inert atmosphere 14.2: 12 h / 20 °C / Inert atmosphere 15.1: sodium tetrahydroborate / isopropyl alcohol / 77 h / 20 - 50 °C / Inert atmosphere View Scheme

1.1: tert.-butyl lithium / diethyl ether; pentane / 0.08 h / -78 °C / Inert atmosphere 1.2: 0.67 h / 0 °C / Inert atmosphere 1.3: 3.5 h / 0 - 20 °C / Inert atmosphere 2.1: 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; [bis(acetoxy)iodo]benzene / dichloromethane / 20 °C / Inert atmosphere 3.1: n-butyllithium; chloro-trimethyl-silane; triethylamine; diisopropylamine / tetrahydrofuran; hexanes / -78 - 20 °C / Inert atmosphere 3.2: 120 °C / Inert atmosphere 4.1: methanol; diethyl ether; benzene / 1.5 h / 6 - 20 °C / Inert atmosphere 5.1: pyridine; hydrogen fluoride / tetrahydrofuran / 24 h / 0 - 20 °C / Inert atmosphere 6.1: pyridinium chlorochromate / dichloromethane / 2.5 h / 0 - 20 °C / Inert atmosphere; Celite 7.1: toluene / 110 °C / Inert atmosphere; Molecular sieve; Sealed tube 7.2: 5.58 h / 0 - 20 °C / Molecular sieve 8.1: PHT / tetrahydrofuran / 72 h / 20 °C / Inert atmosphere 8.2: 12 h / 20 °C / Inert atmosphere 9.1: sodium tetrahydroborate / isopropyl alcohol / 77 h / 20 - 50 °C / Inert atmosphere View Scheme

1.1: zirconocene dichloride; diisobutylaluminium hydride / tetrahydrofuran; n-heptane / 1 h / 0 - 65 °C / Inert atmosphere; Darkness 1.2: 0.25 h / -78 °C / Inert atmosphere 2.1: tert.-butyl lithium / diethyl ether; pentane / 0.08 h / -78 °C / Inert atmosphere 2.2: 0.67 h / 0 °C / Inert atmosphere 2.3: 3.5 h / 0 - 20 °C / Inert atmosphere 3.1: 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; [bis(acetoxy)iodo]benzene / dichloromethane / 20 °C / Inert atmosphere 4.1: n-butyllithium; chloro-trimethyl-silane; triethylamine; diisopropylamine / tetrahydrofuran; hexanes / -78 - 20 °C / Inert atmosphere 4.2: 120 °C / Inert atmosphere 5.1: methanol; diethyl ether; benzene / 1.5 h / 6 - 20 °C / Inert atmosphere 6.1: pyridine; hydrogen fluoride / tetrahydrofuran / 24 h / 0 - 20 °C / Inert atmosphere 7.1: pyridinium chlorochromate / dichloromethane / 2.5 h / 0 - 20 °C / Inert atmosphere; Celite 8.1: toluene / 110 °C / Inert atmosphere; Molecular sieve; Sealed tube 8.2: 5.58 h / 0 - 20 °C / Molecular sieve 9.1: PHT / tetrahydrofuran / 72 h / 20 °C / Inert atmosphere 9.2: 12 h / 20 °C / Inert atmosphere 10.1: sodium tetrahydroborate / isopropyl alcohol / 77 h / 20 - 50 °C / Inert atmosphere View Scheme

1.1: tert.-butyl lithium / diethyl ether; pentane / 0.08 h / -78 °C / Inert atmosphere 1.2: 0.67 h / 0 °C / Inert atmosphere 1.3: 3.5 h / 0 - 20 °C / Inert atmosphere 2.1: 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; [bis(acetoxy)iodo]benzene / dichloromethane / 20 °C / Inert atmosphere 3.1: n-butyllithium; chloro-trimethyl-silane; triethylamine; diisopropylamine / tetrahydrofuran; hexanes / -78 - 20 °C / Inert atmosphere 3.2: 120 °C / Inert atmosphere 4.1: methanol; diethyl ether; benzene / 1.5 h / 6 - 20 °C / Inert atmosphere 5.1: pyridine; hydrogen fluoride / tetrahydrofuran / 24 h / 0 - 20 °C / Inert atmosphere 6.1: pyridinium chlorochromate / dichloromethane / 2.5 h / 0 - 20 °C / Inert atmosphere; Celite 7.1: toluene / 110 °C / Inert atmosphere; Molecular sieve; Sealed tube 7.2: 5.58 h / 0 - 20 °C / Molecular sieve 8.1: PHT / tetrahydrofuran / 72 h / 20 °C / Inert atmosphere 8.2: 12 h / 20 °C / Inert atmosphere 9.1: sodium tetrahydroborate / isopropyl alcohol / 77 h / 20 - 50 °C / Inert atmosphere View Scheme

1.1: 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; [bis(acetoxy)iodo]benzene / dichloromethane / 20 °C / Inert atmosphere 2.1: n-butyllithium; chloro-trimethyl-silane; triethylamine; diisopropylamine / tetrahydrofuran; hexanes / -78 - 20 °C / Inert atmosphere 2.2: 120 °C / Inert atmosphere 3.1: methanol; diethyl ether; benzene / 1.5 h / 6 - 20 °C / Inert atmosphere 4.1: pyridine; hydrogen fluoride / tetrahydrofuran / 24 h / 0 - 20 °C / Inert atmosphere 5.1: pyridinium chlorochromate / dichloromethane / 2.5 h / 0 - 20 °C / Inert atmosphere; Celite 6.1: toluene / 110 °C / Inert atmosphere; Molecular sieve; Sealed tube 6.2: 5.58 h / 0 - 20 °C / Molecular sieve 7.1: PHT / tetrahydrofuran / 72 h / 20 °C / Inert atmosphere 7.2: 12 h / 20 °C / Inert atmosphere 8.1: sodium tetrahydroborate / isopropyl alcohol / 77 h / 20 - 50 °C / Inert atmosphere View Scheme

1.1: n-butyllithium; chloro-trimethyl-silane; triethylamine; diisopropylamine / tetrahydrofuran; hexanes / -78 - 20 °C / Inert atmosphere 1.2: 120 °C / Inert atmosphere 2.1: methanol; diethyl ether; benzene / 1.5 h / 6 - 20 °C / Inert atmosphere 3.1: pyridine; hydrogen fluoride / tetrahydrofuran / 24 h / 0 - 20 °C / Inert atmosphere 4.1: pyridinium chlorochromate / dichloromethane / 2.5 h / 0 - 20 °C / Inert atmosphere; Celite 5.1: toluene / 110 °C / Inert atmosphere; Molecular sieve; Sealed tube 5.2: 5.58 h / 0 - 20 °C / Molecular sieve 6.1: PHT / tetrahydrofuran / 72 h / 20 °C / Inert atmosphere 6.2: 12 h / 20 °C / Inert atmosphere 7.1: sodium tetrahydroborate / isopropyl alcohol / 77 h / 20 - 50 °C / Inert atmosphere View Scheme

1.1: pyridine; hydrogen fluoride / tetrahydrofuran / 24 h / 0 - 20 °C / Inert atmosphere 2.1: pyridinium chlorochromate / dichloromethane / 2.5 h / 0 - 20 °C / Inert atmosphere; Celite 3.1: toluene / 110 °C / Inert atmosphere; Molecular sieve; Sealed tube 3.2: 5.58 h / 0 - 20 °C / Molecular sieve 4.1: PHT / tetrahydrofuran / 72 h / 20 °C / Inert atmosphere 4.2: 12 h / 20 °C / Inert atmosphere 5.1: sodium tetrahydroborate / isopropyl alcohol / 77 h / 20 - 50 °C / Inert atmosphere View Scheme

1.1: methanol; diethyl ether; benzene / 1.5 h / 6 - 20 °C / Inert atmosphere 2.1: pyridine; hydrogen fluoride / tetrahydrofuran / 24 h / 0 - 20 °C / Inert atmosphere 3.1: pyridinium chlorochromate / dichloromethane / 2.5 h / 0 - 20 °C / Inert atmosphere; Celite 4.1: toluene / 110 °C / Inert atmosphere; Molecular sieve; Sealed tube 4.2: 5.58 h / 0 - 20 °C / Molecular sieve 5.1: PHT / tetrahydrofuran / 72 h / 20 °C / Inert atmosphere 5.2: 12 h / 20 °C / Inert atmosphere 6.1: sodium tetrahydroborate / isopropyl alcohol / 77 h / 20 - 50 °C / Inert atmosphere View Scheme

1.1: pyridinium chlorochromate / dichloromethane / 2.5 h / 0 - 20 °C / Inert atmosphere; Celite 2.1: toluene / 110 °C / Inert atmosphere; Molecular sieve; Sealed tube 2.2: 5.58 h / 0 - 20 °C / Molecular sieve 3.1: PHT / tetrahydrofuran / 72 h / 20 °C / Inert atmosphere 3.2: 12 h / 20 °C / Inert atmosphere 4.1: sodium tetrahydroborate / isopropyl alcohol / 77 h / 20 - 50 °C / Inert atmosphere View Scheme

1.1: toluene / 110 °C / Inert atmosphere; Molecular sieve; Sealed tube 1.2: 5.58 h / 0 - 20 °C / Molecular sieve 2.1: PHT / tetrahydrofuran / 72 h / 20 °C / Inert atmosphere 2.2: 12 h / 20 °C / Inert atmosphere 3.1: sodium tetrahydroborate / isopropyl alcohol / 77 h / 20 - 50 °C / Inert atmosphere View Scheme