N-(4-氨丁基)-2-硝基苯磺酰胺合成路线 (共 3 条)
反应条件
in ethanol T=-20°C; Condensation;
参考文献
Hidai; Kan; Fukuyama
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 10 p. 1570 - 1576
反应条件
triethylamine in dichloromethane; chloroform; water
参考文献
Isis Pharmaceuticals, Inc.
Patent: US6191273 B1, 2001 ;
反应条件
N-ethyl-N,N-diisopropylamine; triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran; toluene Fukuyama-Mitsunobu solid-phase alkylation;
参考文献
Tetrahedron, , vol. 61, # 25 p. 6046 - 6055