N-乙酰基-D-苯基丙氨酸甲酯合成路线 （共 16 条）
反应条件
Rhizomucor miehei lipase in acetonitrile T=30°C; 24 h; Inert atmosphereEnzymatic reaction; SolventTimeTemperature; enantioselective reaction;
参考文献
Da Silva, Marcos Reinaldo; De Mattos, Marcos Carlos; De Oliveira, Maria Da Conceicao Ferreira; De Lemos, Telma Leda Gomes; Ricardo, Nagila Maria Pontes Silva; De Gonzalo, Gonzalo; Lavandera, Ivan; Gotor-Fernandez, Vicente; Gotor, Vicente
Tetrahedron, 2014 , vol. 70, # 13 p. 2264 - 2271
反应条件
Rhizomucor miehei lipase in tert-butyl methyl ether T=30°C; 8 h; Inert atmosphereEnzymatic reaction; Solvent; enantioselective reaction;
参考文献
Da Silva, Marcos Reinaldo; De Mattos, Marcos Carlos; De Oliveira, Maria Da Conceicao Ferreira; De Lemos, Telma Leda Gomes; Ricardo, Nagila Maria Pontes Silva; De Gonzalo, Gonzalo; Lavandera, Ivan; Gotor-Fernandez, Vicente; Gotor, Vicente
Tetrahedron, 2014 , vol. 70, # 13 p. 2264 - 2271
参考文献
Chenevert, Robert; Rhlid, Rachid Bel; Letourneau, Martin; Gagnon, Rene; D'Astous, Linda
Tetrahedron: Asymmetry, 1993 , vol. 4, # 6 p. 1137 - 1140
反应条件
lithium hydroxide hydrate in methanol T=20°C; 2 h;
参考文献
Bressi, Jerome C.; Jong, Ron de; Wu, Yiqin; Jennings, Andy J.; Brown, Jason W.; O'Connell, Shawn; Tari, Leslie W.; Skene, Robert J.; Vu, Phong; Navre, Marc; Cao, Xiaodong; Gangloff, Anthony R.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 10 p. 3138 - 3141
反应条件
Streptomyces spp. 82F2 D-aminopeptidase in dimethyl sulfoxide T=25°C; pH=9; 1 h; aq. bufferEnzymatic reaction;
参考文献
Arima, Jiro; Ito, Hitomi; Hatanaka, Tadashi; Mori, Nobuhiro
Biochimie, 2011 , vol. 93, # 9 p. 1460 - 1469
反应条件
Streptomyces spp. 82F2 D-aminopeptidase in dimethyl sulfoxide T=25°C; pH=9; 1 h; aq. bufferEnzymatic reaction;
参考文献
Arima, Jiro; Ito, Hitomi; Hatanaka, Tadashi; Mori, Nobuhiro
Biochimie, 2011 , vol. 93, # 9 p. 1460 - 1469
反应条件
subtilisin-CLEC in acetone T=40°C; 0.5 h; pH 7.0, phosphate buffer; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Wang, Yi-Fong; Yakovlevsky, Kirill; Zhang, Bailing; Margolin, Alexey L.
Journal of Organic Chemistry, 1997 , vol. 62, # 11 p. 3488 - 3495
反应条件
Streptomyces spp. 83D12 D-aminopeptidase in dimethyl sulfoxide T=20°C; pH=6.5; 0.0833333 h; aq. bufferEnzymatic reaction;
参考文献
Bhalerao; Rao; Fadnavis
Synthetic Communications, 1994 , vol. 24, # 15 p. 2109 - 2118
反应条件
modified subtilisin Carlsberg Type VIII in carbon dioxide; water T=47°C; P=85329.4 Torr;
参考文献
Smallridge, Andrew J.; Trewhella, Maurie A.; Wang
Australian Journal of Chemistry, 2002 , vol. 55, # 4 p. 259 - 262
反应条件
sodium hydroxide in water Alcalase, pH 7.5;
参考文献
Tyagi, O D; Boll, P M; Parmar, V S; Taneja, Poonam; Singh, S K
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1992 , vol. 31, # 12 p. 851 - 854
