反应条件
1: 1.) LiNH2 / 1.) THF, 1 h
2: 92 percent / Na, NH3(liq.) / diethyl ether
3: toluene / 48 h / Heating
4: 0.1 N HCl / Ambient temperature
5: toluene / pH = 8.4; buffer: LiOH, 85percent aq. H3PO4, CH3COOH, B(OH)3
6: 70 percent / Red-Al, CuBr / tetrahydrofuran; benzene / 1.) -78 deg C -> -20 deg C, 10 min., 2.) -20 deg C, 1.5 h
View Scheme
参考文献
Bestmann, Hans Juergen; Schobert, Rainer
Synthesis, 1989 , # 6 p. 419 - 423
