3,5-二氯-4-异噻唑甲腈合成路线 （共 9 条）
反应条件
chlorine in tetrachloromethane
参考文献
Hatchard,W.R.
Journal of Organic Chemistry, 1964 , vol. 29, p. 660 - 665
反应条件
(i) Na2S, MeOH, H2O, (ii) /BRN= 969135/; Multistep reaction;
参考文献
Hatchard,W.R.
Journal of Organic Chemistry, 1964 , vol. 29, p. 660 - 665
反应条件
18-crown-6 ether; potassium carbonate; palladium diacetate in toluene T=110°C; Suzuki coupling; 2 h;
参考文献
Christoforou, Irene C.; Koutentis, Panayiotis A.; Rees, Charles W.
Organic and Biomolecular Chemistry, 2003 , vol. 1, # 16 p. 2900 - 2907
反应条件
potassium fluoride; 18-crown-6 ether; palladium diacetate in toluene T=110°C; Suzuki coupling; 3 h;
参考文献
Christoforou, Irene C.; Koutentis, Panayiotis A.; Rees, Charles W.
Organic and Biomolecular Chemistry, 2003 , vol. 1, # 16 p. 2900 - 2907
反应条件
bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran T=60°C; Negishi coupling;
参考文献
Christoforou, Irene C.; Koutentis, Panayiotis A.
Organic and Biomolecular Chemistry, 2006 , vol. 4, # 19 p. 3681 - 3693
反应条件
palladium diacetate in N,N-dimethyl-formamide T=20 - 100°C; Stille coupling; 23 h;
参考文献
Christoforou, Irene C.; Koutentis, Panayiotis A.
Organic and Biomolecular Chemistry, 2006 , vol. 4, # 19 p. 3681 - 3693
反应条件
potassium fluoride; 18-crown-6 ether; palladium diacetate in toluene T=110°C; Suzuki coupling; 77 h;
参考文献
Christoforou, Irene C.; Koutentis, Panayiotis A.; Rees, Charles W.
Organic and Biomolecular Chemistry, 2003 , vol. 1, # 16 p. 2900 - 2907
反应条件
potassium fluoride; 18-crown-6 ether; palladium diacetate in benzene
T=80°C; Suzuki coupling; 2 h;
参考文献
Christoforou, Irene C.; Koutentis, Panayiotis A.; Rees, Charles W.
Organic and Biomolecular Chemistry, 2003 , vol. 1, # 16 p. 2900 - 2907
参考文献
Hatchard,W.R.
Journal of Organic Chemistry, 1964 , vol. 29, p. 660 - 665
