1-(2-氨基苯并[d]噻唑-6-基)乙酮合成路线 （共 4 条）
反应条件
1: With acetic acid 0.25 - 0.333333 h; 2: With bromine; acetic acid T=20°C; 19.3333 h; 3: With ammonia in water pH=9 - 10;
参考文献
Keyes, Robert F.; Gu, Yu gui; Sham, Hing L.
Patent: US2007/219258 A1, 2007 ;
Location in patent: Page/Page column 19 ;
反应条件
1: With bromine; acetic acid T=10 - 50°C; 5 h; 2: With sodium hydroxide in water pH=9 - 10;
参考文献
AstraZeneca AB
Patent: US2011/98292 A1, 2011 ;
Location in patent: Page/Page column 10 ;
反应条件
1: bromine; acetic acid 2: aqueous H2SO4 View Scheme
参考文献
BASF Aktiengesellschaft Ludwigshafen, Germany
Patent: US2003/153568 A1, 2003 ;
参考文献
Ricci; Cagnoli
Annali di Chimica (Rome, Italy), 1955 , vol. 45, p. 172,175
