2-氨基-5-氟-3-硝基吡啶合成路线 （共 3 条）
反应条件
nitric acid in methanol; diethyl ether; dichloromethane; sulfuric acid; Petroleum ether
参考文献
AstraZeneca AB
Patent: US6265415 B1, 2001 ;
US 6265415 B1
反应条件
1: With hydrogenchloride; sodium nitrite in water T=-15 - 20°C; 2.16667 h; 2: With sodium hydroxide in water cooling with ice;
参考文献
Daiichi Sankyo Company, Limited
Patent: EP2471792 A1, 2012 ;
Location in patent: Page/Page column 39-40 ;
反应条件
hydrogenchloride in ethanol; water
参考文献
AstraZeneca AB
Patent: US6265415 B1, 2001 ;
US 6265415 B1
