6-氨基-3-甲基尿嘧啶合成路线 （共 12 条）
反应条件
1: 6-amino-2,4(1H,3H)-pyrimidinedione With ammonium sulfate; lithium hexamethyldisilazane 2 h; Reflux; 2: methyl iodide in toluene 1.5 h; Reflux; 3: With water; sodium thiosulfate T=20°C;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 18, # 5 p. 2001 - 2009
反应条件
sodium hydroxide 2 h; Heating;
参考文献
Roehrkasten; Raatz; Kreher; Blaszkewicz
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 1997 , vol. 52, # 12 p. 1526 - 1532
参考文献
Muller
Tetrahedron Letters, 1991 , vol. 32, # 45 p. 6539 - 6540
参考文献
Chemische Berichte, , vol. 90, p. 2272,2275
反应条件
in methanol 2 h; Heating1) Acetonitrile, 25-30 deg C, 1-3 d; 2) Methanol, reflux, 2 h; Yield given;
参考文献
Liebigs Annalen der Chemie, , p. 1101 - 1106
反应条件
acetic anhydride und anschliessenden Behandeln mit wss.NaOH;
参考文献
Meditsinskaya Promyshlennost SSSR, , vol. 12, # 9 p. 16,20
Chem.Abstr., , p. 16146
反应条件
1: 95 percent / aq. NaOAc, AcOH, NaNO2 / 0.5 h / 100 °C 2: 82 percent / H2, NaOH / 10percent Pd/C / methanol; H2O / 20 °C / 2625.2 Torr 3: 97 percent / NaOAc, glacial AcOH / 3 h / Heating View Scheme
参考文献
Roehrkasten; Raatz; Kreher; Blaszkewicz
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 1997 , vol. 52, # 12 p. 1526 - 1532
反应条件
1: 84 percent / NaNO2, conc. HCl / dimethylformamide; H2O / 1 h / 30 °C 2: Na2S2O4, 12.5percent aq. NH4OH / 0.33 h / 70 °C 3: 4 h / Heating View Scheme
参考文献
Muller
Synthesis, 1993 , # 1 p. 125 - 128
反应条件
sodium acetate; acetic acid; sodium nitrite T=100°C; 0.5 h;
参考文献
Roehrkasten; Raatz; Kreher; Blaszkewicz
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 1997 , vol. 52, # 12 p. 1526 - 1532
反应条件
hydrogenchloride; sulfuric acid
参考文献
Hepner; Frenkenberg
Helvetica Chimica Acta, 1932 , vol. 15, p. 350,352
