bis(η3-allyl-μ-chloropalladium(II)); 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in 1,3,5-trimethyl-benzene T=20 - 140°C; 16.1667 h; Inert atmosphereSealed tube; chemoselective reaction;

sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride T=30 - 40°C;

1: potassium tert-butylate / ethanol; water / Inert atmosphere; Heating 2: bis(η3-allyl-μ-chloropalladium(II)); 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene / 1,3,5-trimethyl-benzene / 16.17 h / 20 - 140 °C / Inert atmosphere; Sealed tube View Scheme

(i) aq. <PhCH2NEt3>Cl, (ii) NaOMe, PhCHO, MeOH; Multistep reaction;