1-(4-甲氧基苯基)-3-二甲氨基-1-丙酮盐酸盐合成路线 （共 15 条）
反应条件
hydrogenchloride in ethanol Mannich reaction; 3 h; Heating;
参考文献
Brahmbhatt; Pandya
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2001 , vol. 40, # 5 p. 419 - 421
反应条件
in acetonitrile T=45 - 509°C; 2 h;
参考文献
Dimmock, Jonathan R.; Patil, Shirish A.; Leek, Donald M.; Warrington, Robert C.; Fang, Wei D.
European Journal of Medicinal Chemistry, 1987 , vol. 22, p. 545 - 552
反应条件
hydrogenchloride in ethanol T=60°C; Mannich reaction;
参考文献
Heterocyclic Communications, , vol. 11, # 2 p. 135 - 138
反应条件
in ethanol; water 16 h; Heating;
参考文献
Ogata, Masaru; Matsumoto, Hiroshi; Kida, Shiro; Shimizu, Sumio; Tawara, Katsuya; Kawamura, Yoshimi
Journal of Medicinal Chemistry, 1987 , vol. 30, # 8 p. 1497 - 1502
反应条件
1: ethanol; H2O / 16 h / Heating 2: Ac2O / 1.5 h / 60 °C View Scheme
参考文献
Ogata, Masaru; Matsumoto, Hiroshi; Kida, Shiro; Shimizu, Sumio; Tawara, Katsuya; Kawamura, Yoshimi
Journal of Medicinal Chemistry, 1987 , vol. 30, # 8 p. 1497 - 1502
反应条件
in ethanol Cyclocondensation; 12 h; Heating;
参考文献
Graef, Edgar; Troschuetz, Reinhard
Synthesis, 1999 , # 7 p. 1216 - 1222
反应条件
ethanol; nickel T=80°C; P=58840.6 Torr; Hydrogenation;
参考文献
Journal of the American Chemical Society, , vol. 75, p. 1128
反应条件
potassium tert-butylate
参考文献
Novello et al.
Journal of the American Chemical Society, 1953 , vol. 75, p. 1330,1334
反应条件
bei der Destillation unter vermindertem Druck;
参考文献
Dimmock; Shyam; Smith
Pharmazie, 1984 , vol. 39, # 7 p. 467 - 470
反应条件
1: NaBH4 / methanol; H2O / 6 h
2: 94 percent / benzene / Ambient temperature
View Scheme
参考文献
Avramova; Dryanovska; Ilarionov
Pharmazie, 1983 , vol. 38, # 7 p. 443 - 444
