5-氨基-1-异丙基-1H-吡唑-4-甲腈合成路线 （共 4 条）
反应条件
N-ethyl-N,N-diisopropylamine in ethanol T=20°C;
参考文献
Pfizer Inc.
Patent: US2010/190771 A1, 2010 ;
Location in patent: Page/Page column 17 ;
参考文献
Schmidt et al.
Helvetica Chimica Acta, 1958 , vol. 41, p. 1052,1056
Helvetica Chimica Acta, 1959 , vol. 42, p. 349,354
反应条件
2: 200 °C 3: POCl3 View Scheme
参考文献
Schmidt et al.
Helvetica Chimica Acta, 1958 , vol. 41, p. 1052,1056
Helvetica Chimica Acta, 1959 , vol. 42, p. 349,354
反应条件
1: With sulfuric acid T=20°C; 2 h; 2: With ammonium hydroxide in water pH=9; Cooling with ice;
参考文献
Pfizer Inc.
Patent: US2010/190771 A1, 2010 ;
Location in patent: Page/Page column 17 ;
