212557-00-1合成路线

参考文献

Bhat, Chinmay; Tilve, Santosh G.
Tetrahedron, 2013 , vol. 69, # 51 p. 10876 - 10883

28697-11-2(S)-(-)-1-Cbz-2-哌啶甲酸

212557-00-1

参考文献

Astellas Pharma Inc.
Patent: WO2009/131246 A1, 2009 ;
Location in patent: Page/Page column 85 ;

41373-39-1+

501-53-1氯甲酸苄酯

212557-00-1

参考文献

Bhat, Chinmay; Tilve, Santosh G.
Tetrahedron, 2013 , vol. 69, # 30 p. 6129 - 6143

123-20-6正丁酸乙烯酯+

105706-75-01-N-苄氧羰基-2-羟甲基哌啶

212557-00-1+

154499-13-5(2R)-2-(羟基甲基)哌啶-1-羧酸苄酯

参考文献

Salgado, Antonio; Mann, Enrique; Sanchez-Sancho, Francisco; Herradon, Bernardo
Heterocycles, 2003 , vol. 60, # 1 p. 57 - 71

3105-95-1L-哌啶-2-甲酸

212557-00-1

参考文献

Bhat, Chinmay; Tilve, Santosh G.
Tetrahedron, 2013 , vol. 69, # 51 p. 10876 - 10883

60369-19-9(2R)-1,2-哌啶二羧酸 2-甲基 1-(苯基甲基)酯

212557-00-1

参考文献

Gomez, Livia; Garrabou, Xavier; Joglar, Jesus; Bujons, Jordi; Parella, Teodor; Vilaplana, Cristina; Cardona, Pere Joan; Clapes, Pere
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 31 p. 6309 - 6321

123-20-6正丁酸乙烯酯+

105706-75-01-N-苄氧羰基-2-羟甲基哌啶

212557-00-1+

154499-13-5(2R)-2-(羟基甲基)哌啶-1-羧酸苄酯

参考文献

Salgado, Antonio; Mann, Enrique; Sanchez-Sancho, Francisco; Herradon, Bernardo
Heterocycles, 2003 , vol. 60, # 1 p. 57 - 71

501-53-1氯甲酸苄酯

212557-00-1

参考文献

Gurjar; Ghosh, Lakshmi; Syamala; Jayasree
Tetrahedron Letters, 1994 , vol. 35, # 47 p. 8871 - 8872

3433-37-22-哌啶甲醇

212557-00-1

参考文献

Sanchez-Sancho, Francisco; Herradon, Bernardo
Tetrahedron Asymmetry, 1998 , vol. 9, # 11 p. 1951 - 1965

28697-07-61-N-Cbz-2-哌啶甲酸

212557-00-1

参考文献

Coppola, Gary M.; Damon, Robert E.; Eskesen, J. Bruce; France, Dennis S.; Paterniti Jr., James R.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 3 p. 809 - 812