吗啉-3,4-二羧酸- -4-叔丁酯-3-甲酯合成路线 （共 3 条）
反应条件
potassium carbonate in DMF (N,N-dimethyl-formamide) T=20°C; 4 h;
参考文献
ASTRAZENECA AB; NPS PHARMACEUTICALS, INC.
Patent: WO2005/80386 A1, 2005 ;
Location in patent: Page/Page column 41-42 ;
WO 2005/080386 A1
反应条件
methanol in hexanes T=0 - 20°C;
参考文献
EVOTEC NEUROSCIENCES GMBH
Patent: WO2008/125570 A1, 2008 ;
Location in patent: Page/Page column 47 ;
WO 2008/125570 A1
反应条件
1: With lithium borohydride in tetrahydrofuran T=0 - 20°C; 2: With hydrogenchloride; water in tetrahydrofuran
参考文献
WO2008/125570 A1, ;
Page/Page column 47-48 ;
WO 2008/125570 A1
