2-(吡啶-4-基)噻唑-4-羧酸乙酯合成路线 （共 3 条）
参考文献
Rzasa, Robert M.; Kaller, Matthew R.; Liu, Gang; Magal, Ella; Nguyen, Thomas T.; Osslund, Timothy D.; Powers, David; Santora, Vincent J.; Viswanadhan, Vellarkad N.; Wang, Hui-Ling; Xiong, Xiaoling; Zhong, Wenge; Norman, Mark H.
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 20 p. 6574 - 6595
反应条件
sodium hydroxide; water in ethanol T=80°C;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 15, # 20 p. 6574 - 6595
反应条件
1: With diisobutylaluminium hydride in dichloromethane
T=0°C; 1 h;
2: With acetic acid in dichloromethane
T=0 - 25°C;
参考文献
Randolph, John T.; Chen, Hui-Ju; DeGoey, David A.; Flentge, Charles A.; Flosi, William J.; Grampovnik, David J.; Huang, Peggy P.; Hutchinson, Douglas K.; Kempf, Dale J.; Klein, Larry L.; Yeung, Ming C.
Patent: US2005/159469 A1, 2005 ;
Location in patent: Page/Page column 104 ;
US 20050159469 A1
