Boc-O-苄基-L-酪氨酸合成路线 (共 34 条)
参考文献
Zeitschrift fuer Chemie (Stuttgart, Germany), , vol. 13, p. 221 - 222
反应条件
(i) aq. K2CO3, (ii) /BRN= 1363586/, Py, (iii) aq. NaOH; Multistep reaction;
参考文献
Chemische Berichte, , vol. 97, p. 3298 - 3304
反应条件
C20H29N4O5Pol in tetrahydrofuran; dichloromethane efffect of temp. and reagents (as imidazole, N-hydroxybenztriazole); Product distribution;
参考文献
Shai, Yechiel; Jacobson, Kenneth A.; Patchornik, Abraham
Journal of the American Chemical Society, 1985 , vol. 107, # 14 p. 4249 - 4252
反应条件
1: 79 percent / dimethylaminopyridine, 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride / CH2Cl2 / 14 h / Ambient temperature 2: 98 percent / 4 N HCl / dioxane / Ambient temperature View Scheme
参考文献
Ikeda, Kiyoshi; Miyajima, Keisuke; Maruyama, Yasufumi; Achiwa, Kazuo
Chemical and Pharmaceutical Bulletin, 1999 , vol. 47, # 4 p. 563 - 568
反应条件
hydrogen in ethanol 0.75 h;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 8 p. 2597 - 2601
反应条件
1: diethyl ether / Ambient temperature 2: LiAlH4 / tetrahydrofuran / 1 h / 0 °C 3: 90 percent / pyridine / Ambient temperature 4: 23 percent / aq. K2S2O8, aq. CuSO4 / acetonitrile / 1.67 h / Heating View Scheme
参考文献
Kawamine; Takeuchi; Miyashita; Irie; Shimamoto; Ohfune
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 12 p. 3170 - 3171
反应条件
1: 73 percent / dimethylformamide / 15 h / 20 °C 2: H2 / Pd/C / methanol / 2 h / 20 °C View Scheme
参考文献
Sajiki, Hironao; Hirota, Kosaku
Tetrahedron, 1998 , vol. 54, # 46 p. 13981 - 13996
反应条件
pentafluorophenyl diphenyl-phosphinate; N-ethyl-N,N-diisopropylamine Yield given. Multistep reaction;
参考文献
Chen, Shaoqing; Xu, Jiecheng
Tetrahedron Letters, 1991 , vol. 32, # 46 p. 6711 - 6714
反应条件
trimethylsilyl trifluoromethanesulfonate; methyl-phenyl-thioether in trifluoroacetic acid T=0°C; 0.5 h;
参考文献
Fujii; Otaka; Ikemura; Hatano; Okamachi; Funakoshi; Sakurai; Shioiri; Yajima
Chemical and pharmaceutical bulletin, 1987 , vol. 35, # 8 p. 3447 - 3452
反应条件
4-methyl-morpholine in tetrahydrofuran; acetonitrile Ambient temperature;
参考文献
Jaoudai, Mahmoud; Martinez, Jean; Castro, Bertrand
Journal of Organic Chemistry, 1987 , vol. 52, # 12 p. 2364 - 2367