Boc-O-苄基-L-酪氨酸合成路线 （共 34 条）
反应条件
4-methyl-morpholine; hydrogenchloride; sodium tetrahydroborate in tetrahydrofuran; methanol
参考文献
Abbott Laboratories
Patent: US6274715 B1, 2001 ;
反应条件
1: N-methylmorpholine / tetrahydrofuran / -15 °C
2: NaBH4 / methanol; tetrahydrofuran / 1.5 h
3: Me3SiCl; PhOH / CH2Cl2 / 1 h / 20 °C
View Scheme
参考文献
Mavridis, Ioannis; Kythreoti, Georgia; Koltsida, Konstantina; Vourloumis, Dionisios
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 4 p. 1329 - 1341
反应条件
thionyl chloride
18 h;
参考文献
Heasley, Brian H.; Jarosz, Renata; Lynch, Kevin R.; Macdonald, Timothy L.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 11 p. 2735 - 2740
反应条件
Yield given. Multistep reaction;
参考文献
Stetler-Stevenson, Mary Alice; Yang, Dai Chang; Lipkowski, Andrew; McCartney, Linda; Peterson, Darryl; Fluoret, George
Journal of Medicinal Chemistry, 1981 , vol. 24, # 6 p. 688 - 692
