(2-氨基-4-甲氧基苯基)氨基甲酸叔丁酯合成路线 （共 8 条）
反应条件
hydrogen; palladium on activated charcoal in methanol T=20°C; 9 h;
参考文献
EP2107052 A1, ;
Page/Page column 32 ;
反应条件
iodine in methanol T=20°C; 1 h;
参考文献
WO2012/3418 A2, ;
Page/Page column 70-71 ;
WO 2012/003418 A2
反应条件
sodium tetrahydroborate in methanol T=20°C; 0.75 h;
参考文献
Organic Letters, , vol. 12, # 7 p. 1492 - 1495
反应条件
1: thionyl chloride, DMF / toluene / 0.5 h / Heating 2: aq. NaN3 / acetone / 1 h 3: 0.17 h / Heating 4: H2 / 10percent Pd/C / ethanol / 3 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 40, # 4 p. 586 - 593
反应条件
1: aq. NaN3 / acetone / 1 h 2: 0.17 h / Heating 3: H2 / 10percent Pd/C / ethanol / 3 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 40, # 4 p. 586 - 593
反应条件
1: 50 percent / 50percent NaH in oil / tetrahydrofuran; dioxane / Heating 2: 3.5 g / hydrogen / 10percent Pd/C / methanol / 2280 Torr View Scheme
参考文献
Heterocycles, , vol. 48, # 7 p. 1347 - 1363
反应条件
1: 50 percent / 50percent NaH in oil / tetrahydrofuran; dioxane / Heating 2: 3.5 g / hydrogen / 10percent Pd/C / methanol / 2280 Torr View Scheme
参考文献
Heterocycles, , vol. 48, # 7 p. 1347 - 1363
反应条件
potassium carbonate in N,N-dimethyl-formamide T=130°C; 5 h;
参考文献
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL; JIN, Jian; ROTH, Bryan; FRYE, Stephen
Patent: WO2012/3418 A2, 2012 ;
Location in patent: Page/Page column 71 ;
WO 2012/003418 A2
