林可霉素 2,7-二乙酸酯合成路线 （共 119 条）
反应条件
potassium phosphate; triphenylphosphine; palladium diacetate in dimethyl sulfoxide T=80°C; 48 h;
参考文献
Shirakawa, Eiji; Kitabata, Takaaki; Otsuka, Hidehito; Tsuchimoto, Teruhisa
Tetrahedron, 2005 , vol. 61, # 41 p. 9878 - 9885
反应条件
copper(l) iodide; bis(benzonitrile)palladium(II) dichloride; (benzyl)-tri-(butyl)-ammonium chloride; sodium hydroxide; [(t-Bu)3PH]BF4 in water; toluene T=40°C; Sonogashira coupling; 22 h; Inert atmosphere;
参考文献
Bellina, Fabio; Lessi, Marco
Synlett, 2012 , vol. 23, # 5 p. 773 - 777
反应条件
bis-triphenylphosphine-palladium(II) chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,4-di(diphenylphosphino)-butane in dimethyl sulfoxide T=110°C; 3 h;
参考文献
Park, Kyungho; Bae, Goun; Moon, Jeongju; Choe, Jaehoon; Song, Kwang Ho; Lee, Sunwoo
Journal of Organic Chemistry, 2010 , vol. 75, # 18 p. 6244 - 6251
反应条件
pyridine in methanol T=5°C; Irradiation;
参考文献
Journal of the American Chemical Society, , vol. 108, # 10 p. 2641 - 2645
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; ytterbium in tetrahydrofuran T=-10°C; 0.333333 h;
参考文献
Taniguchi, Yuki; Fujii, Nobuto; Makioka, Yoshikazu; Takaki, Ken; Fujiwara, Yuzo
Chemistry Letters, 1993 , # 7 p. 1165 - 1168
反应条件
tetrabutylammomium bromide; palladium dichloride in water T=100°C; 8 h; Title compound not separated from byproducts;
参考文献
Advanced Synthesis and Catalysis, , vol. 348, # 14 p. 1874 - 1882
反应条件
potassium hydroxide; copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride T=80°C;
参考文献
Csekei, Marton; Novak, Zoltan; Kotschy, Andras
Tetrahedron, 2008 , vol. 64, # 6 p. 975 - 982
反应条件
tris[N-(tert-butyl)(3,5-dimethylphenyl)amido]molybdenum(VI) propylidyne; tris(2-hydroxy-5-nitro-benzyl)amine in tetrachloromethane T=20°C; 4 h; Inert atmosphere;
参考文献
Jyothish, Kuthanapillil; Zhang, Wei
Angewandte Chemie - International Edition, 2011 , vol. 50, # 15 p. 3435 - 3438
反应条件
[bis(acetoxy)iodo]benzene in dichloromethane T=20°C; 18 h; IrradiationGreen chemistry;
参考文献
Li, Jinming; Chen, Huiyu; Zhang-Negrerie, Daisy; Du, Yunfei; Zhao, Kang
RSC Advances, 2013 , vol. 3, # 13 p. 4311 - 4320
反应条件
{(Pd{Fe(.eta.5-C5H5)(.eta.5-C5H3C(CH3)=NC6H4CH3-4)}(.mu.-Cl))2}; potassium carbonate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in acetonitrile T=110°C; 16 h; Inert atmosphere;
参考文献
Hu, Hao; Yang, Fan; Wu, Yangjie
Journal of Organic Chemistry, 2013 , vol. 78, # 20 p. 10506 - 10511
