林可霉素 2,7-二乙酸酯合成路线 (共 119 条)
反应条件
lithium aluminium tetrahydride; titanium(III) chloride in tetrahydrofuran 24 h; Heating; Further byproducts given. Title compound not separated from byproducts;
参考文献
Bulletin des Societes Chimiques Belges, , vol. 100, # 5 p. 375 - 380
参考文献
Neunhoeffer, Hans; Bopp, Ralf; Diehl, Werner
Liebigs Annalen der Chemie, 1993 , # 4 p. 367 - 374
反应条件
Raney-Nickel W-2B in benzene 2.5 h; Heating;
参考文献
Latif, K. A.; Ali, M. Umar
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 5 p. 471 - 473
反应条件
pyridine; copper diacetate T=5°C; Irradiationinvestigation effect of present or absent of pyridine and various Cu(II) salts; Product distribution;
参考文献
Journal of the American Chemical Society, , vol. 108, # 10 p. 2641 - 2645
反应条件
lithium aluminium tetrahydride; titanium(III) chloride in tetrahydrofuran 24 h; Heating; Further byproducts given. Title compound not separated from byproducts;
参考文献
Bulletin des Societes Chimiques Belges, , vol. 100, # 5 p. 375 - 380
反应条件
n-butyllithium 1.) hexane, THF, benzene, -70 deg C, 20 min, 2.) hexane, THF, benzene, from -70 deg C to 0 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Heterocycles, , vol. 26, # 6 p. 1467 - 1470
反应条件
T=180 - 200°C; im Rohr;
参考文献
Journal of the American Chemical Society, , vol. 48, p. 3148
反应条件
monosodium salt of ethylene glycol; ethylene glycol
参考文献
Journal of the Chemical Society, , p. 4210
反应条件
T=180 - 200°C; im Rohr;
参考文献
Journal of the American Chemical Society, , vol. 48, p. 3148
反应条件
T=180 - 200°C; im Rohr;
参考文献
Journal of the American Chemical Society, , vol. 48, p. 3148