2-环己基异吲哚-1,3-二酮合成路线 （共 42 条）
反应条件
palladium diacetate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; trichlorophosphate
T=140°C; 20 h; Inert atmosphere;
参考文献
Sawant, Dinesh N.; Wagh, Yogesh S.; Bhatte, Kushal D.; Bhanage, Bhalchandra M.
European Journal of Organic Chemistry, 2011 , # 33 p. 6719 - 6724
反应条件
palladium diacetate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; trichlorophosphate
T=140°C; 20 h; Inert atmosphere;
参考文献
Sawant, Dinesh N.; Wagh, Yogesh S.; Bhatte, Kushal D.; Bhanage, Bhalchandra M.
European Journal of Organic Chemistry, 2011 , # 33 p. 6719 - 6724
反应条件
sodium hydroxide in water; acetonitrile
T=20°C; 0.5 h; Irradiation; Further byproducts given;
参考文献
Suau, Rafael; Sanchez-Sanchez, Cristobal; Garcia-Segura, Rafael; Perez-Inestrosa, Ezequiel
European Journal of Organic Chemistry, 2002 , # 12 p. 1903 - 1911
反应条件
in N,N-dimethyl acetamide
0.0416667 h;
参考文献
Khajavi, Mohammad S.; Nikpour, Farzad; Hajihadi, Mostafa
Journal of Chemical Research - Part S, 1996 , # 2 p. 96 - 97
反应条件
in acetonitrile
T=100°C; 24 h; Glovebox;
参考文献
Tran, Ba L.; Li, Bijie; Driess, Matthias; Hartwig, John F.
Journal of the American Chemical Society, 2014 , vol. 136, # 6 p. 2555 - 2563
反应条件
1: 86 percent / (C2H5)3N / benzene / 0.05 h / 6 - 7 °C
2: 140 - 160 °C
View Scheme
参考文献
Ganin, E. V.; Makarov, V. F.; Rozynov, B. V.
Journal of Organic Chemistry USSR (English Translation), 1985 , vol. 21, # 9 p. 1772 - 1777
Zhurnal Organicheskoi Khimii, 1985 , vol. 21, # 9 p. 1935 - 1941
反应条件
1: 1.) PyBOP, (i-Pr)2NEt / 1.) THF, r.t., 40 min, 2.) r.t., 30 min
2: 94 percent / p-TsOH / toluene / 4 h / Heating
View Scheme
参考文献
Aguilar, Nuria; Moyano, Albert; Pericas, Miquel A.; Riera, Antoni
Synthesis, 1998 , # 3 p. 313 - 316
反应条件
pyridine; 4-(N,N-dimethlyamino)pyridine; phthalic anhydride
4 h; Heating;
参考文献
Egg; Ganzera; Leibetseder; et al.
Archiv der Pharmazie, 1986 , vol. 319, # 8 p. 682 - 690
反应条件
pyridine; 4-(N,N-dimethlyamino)pyridine
4 h; Heating;
参考文献
Egg; Ganzera; Leibetseder; et al.
Archiv der Pharmazie, 1986 , vol. 319, # 8 p. 682 - 690
反应条件
in toluene
0.25 h; Heating;
参考文献
Andres, Jose Angel; Palomo, Claudio
Bulletin de la Societe Chimique de France, 1982 , vol. 2, # 11-12 p. 369 - 371
