N-(2-氯-3-吡啶)-乙酰胺合成路线 （共 12 条）
反应条件
triethylamine in dichloromethane
参考文献
Caron, Stephane; Massett, Steve S.; Bogle, David E.; Castaldi, Michael J.; Braish, Tamim F.
Organic Process Research and Development, 2001 , vol. 5, # 3 p. 254 - 256
反应条件
acetic acid 1 h; Heating;
参考文献
Zheng, Nan; Anderson, Kevin W.; Huang, Xiaohua; Nguyen, Hanh Nho; Buchwald, Stephen L.
Angewandte Chemie - International Edition, 2007 , vol. 46, # 39 p. 7509 - 7512
反应条件
1: With triethylamine in dichloromethane T=20°C; 2: With sodium hydrogencarbonate in water pH=7;
参考文献
SU, Wei-Guo; JIA, Hong; DAI, Guangxiu
Patent: US2012/245178 A1, 2012 ;
Location in patent: Page/Page column 23 ;
US 20120245178 A1
反应条件
in tetrahydrofuran; ethyl acetate
参考文献
Merck Frosst Canada, Inc.
Patent: US5472964 A1, 1995 ;
US 5472964 A
反应条件
1: concentrated aqueous HCl View Scheme
参考文献
v. Schickh et al.
Chemische Berichte, 1936 , vol. 69, p. 2593,2604
反应条件
1: iron; acetic acid View Scheme
参考文献
v. Schickh et al.
Chemische Berichte, 1936 , vol. 69, p. 2593,2604
反应条件
1: NOCl; acetic acid; acetic acid anhydride / Zusatz von Kaliumacetat und P2O5 2: benzene View Scheme
参考文献
Adams et al.
Journal of the Chemical Society, 1949 , p. 3181,3183
反应条件
1: 1,4-diazabicyclo<2.2.2>octane / toluene 2: 64 percent / 2 N aq. HCl / 1 h / 40 °C View Scheme
参考文献
Andreae, Siegfried; Schmitz, Ernst
Heterocycles, 1994 , vol. 37, # 1 p. 379 - 386
反应条件
sodium hydride 1.) DMF, 0 deg C, 10 min, 2.) 80 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Couture; Grandclaudon
Synthesis, 1991 , # 11 p. 982 - 984
反应条件
sodium hydride
1.) DMF, 0 deg C, 10 min, 2.) 150 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Couture; Grandclaudon
Synthesis, 1991 , # 11 p. 982 - 984
