1-溴-2-苯基乙炔-苯合成路线 （共 49 条）
反应条件
1,3-dimethyl-imidazolidin-2-one; potassium carbonate; triphenylphosphine; copper(l) chloride T=120°C; 12 h;
参考文献
Ogawa, Daisuke; Li, Jing; Suetsugu, Masato; Jiao, Jiao; Iwasaki, Masayuki; Nishihara, Yasushi
Tetrahedron Letters, 2013 , vol. 54, # 6 p. 518 - 521
反应条件
1.1: BuLi / tetrahydrofuran; hexane / 1 h / -78 °C 1.2: tetrahydrofuran; hexane / 1 h 2.1: tetrahydrofuran; hexane / 1 h / 20 °C 3.1: t-BuOK / tetrahydrofuran; hexane / 2 h / 20 °C View Scheme
参考文献
Orita, Akihiro; Yoshioka, Naonori; Struwe, Petra; Braier, Arnold; Beckmann, Anke; Otera, Junzo
Chemistry--A European Journal, 1999 , vol. 5, # 4 p. 1355 - 1363
反应条件
1.1: dimethylformamide 2.1: BuLi / tetrahydrofuran; hexane / 1 h / -78 °C 2.2: tetrahydrofuran; hexane / 1 h 3.1: tetrahydrofuran; hexane / 1 h / 20 °C 4.1: t-BuOK / tetrahydrofuran; hexane / 2 h / 20 °C View Scheme
参考文献
Orita, Akihiro; Yoshioka, Naonori; Struwe, Petra; Braier, Arnold; Beckmann, Anke; Otera, Junzo
Chemistry--A European Journal, 1999 , vol. 5, # 4 p. 1355 - 1363
反应条件
piperidine; silica-supported palladium catalyst T=70°C; Sonogashira coupling; 0.5 h;
参考文献
Tyrrell, Elizabeth; Whiteman, Leon; Williams, Neil
Synthesis, 2009 , # 5 p. 829 - 835
反应条件
(i) Br2, (ii) NaOEt; Multistep reaction;
参考文献
Markl; Jin; Berr
Tetrahedron Letters, 1993 , vol. 34, # 19 p. 3103 - 3106
反应条件
potassium tert-butylate; tert-butyl alcohol
参考文献
Markl; Jin; Berr
Tetrahedron Letters, 1993 , vol. 34, # 19 p. 3103 - 3106
反应条件
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); potassium carbonate Sonogashira coupling; 17 h; Neat (no solvent);
参考文献
Fulmer, Dennis A.; Shearouse, William C.; Medonza, Shareika T.; MacK, James
Green Chemistry, 2009 , vol. 11, # 11 p. 1821 - 1825
反应条件
pyridine 10 h; Heating;
参考文献
Clive, Derrick L. J.; Cole, Derek C.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 12 p. 3263 - 3270
反应条件
2: KOtBu, tBuOH View Scheme
参考文献
Letsinger,R.L. et al.
Journal of Organic Chemistry, 1961 , vol. 26, p. 1271 - 1273
反应条件
2: KOtBu, tBuOH View Scheme
参考文献
Letsinger,R.L. et al.
Journal of Organic Chemistry, 1961 , vol. 26, p. 1271 - 1273
