3-氨基-1-苄基-1H-吡唑-4-羧酸乙酯合成路线 （共 4 条）
反应条件
sodium methylate in N,N-dimethyl-formamide 3 h; Reflux;
参考文献
INDOCO REMEDIES LIMITED; RAJADHYAKSHA, Mangesh, Narayan; KOLEKAR, Shankar, Laxman; BAVISKAR, Anil, Yuvraj; PANANDIKAR, Aditi, Milind
Patent: WO2011/64798 A1, 2011 ;
Location in patent: Page/Page column 8 ;
反应条件
sodium hydride in acetonitrile T=20°C; 12 h;
参考文献
Baviskar, Ashish T.; Banerjee, Uttam C.; Gupta, Mukesh; Singh, Rajveer; Kumar, Sunil; Gupta, Manish K.; Kumar, Sanjeev; Raut, Satish K.; Khullar, Madhu; Singh, Sandeep; Kumar, Raj
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 18 p. 5782 - 5793
反应条件
1: isopropyl alcohol / 3 h / Reflux 2: NH2NH2•xH2O / water / 6 h / 15 - 45 °C 3: sodium methylate / N,N-dimethyl-formamide / 3 h / Reflux View Scheme
参考文献
INDOCO REMEDIES LIMITED; RAJADHYAKSHA, Mangesh, Narayan; KOLEKAR, Shankar, Laxman; BAVISKAR, Anil, Yuvraj; PANANDIKAR, Aditi, Milind
Patent: WO2011/64798 A1, 2011 ;
参考文献
Pharmazie, , vol. 46, # 10 p. 747 - 748
