2-三苯基膦乙烯基丙酸乙酯合成路线 （共 81 条）
反应条件
in chloroform-d1 T=20°C; Rearrangement; cyclopropanation;
参考文献
Avery, Thomas D.; Taylor, Dennis K.; Tiekink, Edward R.T.
Journal of Organic Chemistry, 2000 , vol. 65, # 18 p. 5531 - 5546
反应条件
in toluene T=0 - 20°C; 3 h;
参考文献
Okuro, Kazumi; Alper, Howard
Journal of Organic Chemistry, 2012 , vol. 77, # 9 p. 4420 - 4424
反应条件
triethylamine in dichloromethane 1 h; Ambient temperature;
参考文献
Lang, Robert W.; Hansen, Hans-Juergen
Helvetica Chimica Acta, 1980 , vol. 63, # 2 p. 438 - 455
反应条件
tributyl-amine; 2-chloro-1-methyl-pyridinium iodide in toluene 3 h; Heatingother reagents (bases); Product distribution;
参考文献
Kohl-Mines, Elisabeth; Hansen, Hans-Juergen
Helvetica Chimica Acta, 1985 , vol. 68, p. 2244 - 2248
反应条件
in dichloromethane T=-10°C; 4 h;
参考文献
Journal of the Chemical Society. Perkin Transactions 1, , # 22 p. 3073 - 3079
反应条件
in dichloromethane T=50°C; 28 h;
参考文献
Volkonskii, A. Yu.; Mysov, E. I.; Rokhlin, E. M.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1984 , vol. 33, # 6 p. 1246 - 1257
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1984 , # 6 p. 1356 - 1367
反应条件
manganese(IV) oxide in dichloromethane oxidation-Wittig reaction; 1 h; Heating;
参考文献
Runcie, Karen A.; Taylor, Richard J. K.
Chemical Communications, 2002 , # 9 p. 974 - 975
反应条件
1: methanol; (4S,2Z)-4-methyl-5-trityloxypent-2-ene With toluene-4-sulfonic acid T=20°C; 4 h; 2: With oxalyl dichloride; dimethyl sulfoxide in dichloromethane T=-78°C; Swern oxidation; 0.583333 h; 3: triphenyl(1-[ethoxycarbonyl]ethylidene)phosphorane Further stages;
参考文献
Dunetz, Joshua R.; Julian, Lisa D.; Newcom, Jason S.; Roush, William R.
Journal of the American Chemical Society, 2008 , vol. 130, # 48 p. 16407 - 16416
反应条件
1: methanol; (4S,2Z)-4-methyl-5-trityloxypent-2-ene With toluene-4-sulfonic acid in dichloromethane; water T=20°C; 4 h; Inert atmosphere; 2: With oxalyl dichloride; triethylamine in dichloromethane; dimethyl sulfoxide T=-78 - 0°C; Swern oxidation; 1.75 h; Inert atmosphere; 3: triphenyl(1-[ethoxycarbonyl]ethylidene)phosphorane in dichloromethane; dimethyl sulfoxide T=-78 - 20°C; Inert atmosphere; optical yield given as percent ee;
参考文献
Dunetz, Joshua R.; Roush, William R.
Organic Letters, 2008 , vol. 10, # 10 p. 2059 - 2062
反应条件
(i) Raney-Ni, THF, (ii) KOH, aq. EtOH, (iii) H2, Raney-Ni, aq. MeOH; Multistep reaction;
参考文献
Bestmann,H.J. et al.
Chemische Berichte, 1966 , vol. 99, p. 1906 - 1911
