(1-戊基)三苯基溴化磷合成路线 （共 78 条）
反应条件
1: 1.) NaNH2, HMPA / 1.) THF, RT, 90 min, 2.) THF, from -78 deg C to RT, 5 h
2: 89 percent / CBr4, Ph3P / CH2Cl2 / Ambient temperature
3: 1.) n-BuLi / 1.) hexane, THF, -10 deg C, 30 min, 2.) hexane, THF, HMPA, -10 deg C, 3 h
View Scheme
参考文献
Singh, Vasundhara; Trehan, I. R.; Kad, G. L.
Journal of the Indian Chemical Society, 1992 , vol. 69, # 2 p. 103 - 105
反应条件
sodium hydroxide in water
Heating;
参考文献
Buss, Antony D.; Warren, Stuart
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2307 - 2326
反应条件
1: n-pentyltriphenylphosphonium bromide With potassium tert-butylate in toluene
Dehydrobromination; Heating;
2: 4-methoxycarbonyl-butanal in toluene
T=25°C; Wittig reaction; 2 h;
参考文献
Vinczer, Peter; Novak, Lajos; Szantay, Csaba
Organic Preparations and Procedures International, 1991 , vol. 23, # 4 p. 443 - 447
反应条件
potassium tert-butylate
1.) THF, -30 deg C, 20 min, 2.) THF, a) -78 deg C, 2 h, b) RT, 16 h; Yield given. Multistep reaction;
参考文献
Odinokov, V. N.; Akhmetova, V. R.; Khasanov, Kh. D.; Abduvakhabov, A. A.; Tolstikov, O. A.
Chemistry of Natural Compounds, 1991 , vol. 27, # 4 p. 497 - 499
Khimiya Prirodnykh Soedinenii, 1991 , # 4 p. 568 - 571
反应条件
n-butyllithium
1) THF, hexane, 30 min, room temperature; 2) THF, hexane, room temperature, 3 h; Yield given. Multistep reaction;
参考文献
Aitken, R. Alan; Atherton, J. Ian
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 10 p. 1281 - 1284
反应条件
n-butyllithium
1) THF, hexane, 30 min, room temperature; 2) THF, hexane, room temperature, 3 h; Yield given. Multistep reaction;
参考文献
Aitken, R. Alan; Atherton, J. Ian
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 10 p. 1281 - 1284
反应条件
1: 83.8 percent / NaOH / H2O / Heating
2: 1.) n-BuLi / 1.) hexane, THF, 0 deg C, 30 min; 2.) -78 deg C -> RT
View Scheme
参考文献
Buss, Antony D.; Warren, Stuart
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2307 - 2326
反应条件
1: NaOEt / tetrahydrofuran / 1 h / 25 °C
2: n-BuLi / toluene / 2 h / 25 °C
View Scheme
参考文献
Vinczer, Peter; Juvancz, Zoltan; Novak, Lajos; Szantay, Csaba
Acta Chimica Hungarica, 1988 , vol. 125, # 6 p. 797 - 820
反应条件
sodium hexamethyldisilazane in tetrahydrofuran
1. 1h reflux 2. -78 deg C, 1h 3. 25 deg C, 20h;
参考文献
Vinczer, Peter; Baan, Gabor; Novak, Lajos; Szantay, Csaba
Tetrahedron Letters, 1984 , vol. 25, # 25 p. 2701 - 2704
反应条件
1: NaOEt / tetrahydrofuran / 1 h / 25 °C
2: n-BuLi / toluene / 2 h / 25 °C
View Scheme
参考文献
Vinczer, Peter; Juvancz, Zoltan; Novak, Lajos; Szantay, Csaba
Acta Chimica Hungarica, 1988 , vol. 125, # 6 p. 797 - 820
