3-苄基-7-氯-3H-[1,2,3]-噻唑并[4,5-d]嘧啶合成路线 (共 3 条)
反应条件
thionyl chloride in chloroform; N,N-dimethyl-formamide 3 h; Heating / reflux;
参考文献
Vasopharm Biotech GmbH
Patent: EP1598354 A1, 2005 ;
Location in patent: Page/Page column 88 ;
反应条件
1: ethanol / 8 h / Heating 2: POCl3; N,N-diethylaniline / 6 h / 90 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 13, # 15 p. 4679 - 4693
反应条件
1: EtONa / ethanol / 1 h / Heating 2: ethanol / 8 h / Heating 3: POCl3; N,N-diethylaniline / 6 h / 90 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 13, # 15 p. 4679 - 4693