1.1: dichloromethane / 20 °C 2.1: tri-ruthenium(0)dodecacarbonyl / 3,3-dimethyl-butan-2-one / 24 h / 140 °C / Inert atmosphere 3.1: tetrahydrofuran / 20 °C 3.2: 20 °C 4.1: methyl trifluoromethanesulfonate / dichloromethane / 0 °C 4.2: 6 h / 50 °C View Scheme

1.1: tetrahydrofuran / 20 °C 1.2: 20 °C 2.1: methyl trifluoromethanesulfonate / dichloromethane / 0 °C 2.2: 6 h / 50 °C View Scheme

1.1: tri-ruthenium(0)dodecacarbonyl / 3,3-dimethyl-butan-2-one / 24 h / 140 °C / Inert atmosphere 2.1: tetrahydrofuran / 20 °C 2.2: 20 °C 3.1: methyl trifluoromethanesulfonate / dichloromethane / 0 °C 3.2: 6 h / 50 °C View Scheme

1.1: potassium carbonate; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl / toluene / 16 h / 130 °C / |Inert atmosphere 2.1: tri-ruthenium(0)dodecacarbonyl; 3,3-dimethyl-butan-2-one / 24 h / 140 °C / |Inert atmosphere 3.1: methyl-magnesium chloride / tetrahydrofuran / 0.17 h / 20 °C 3.2: 1 h / 20 °C 4.1: methyl trifluoromethanesulfonate / dichloromethane / 12 h / 0 °C 4.2: 6 h / 50 °C View Scheme

water; sodium t-butanolate in tetrahydrofuran Heating;