2-(叔丁氧羰基氨基)-5-己烯酸合成路线 （共 10 条）
反应条件
1: With N-ethyl-N,N-diisopropylamine in 1,4-dioxane; water T=20°C; Inert atmosphere; 2: With hydrogenchloride in diethyl ether; water
参考文献
Ple, Karen; Haudrechy, Arnaud; Probst, Nicolas P.
Tetrahedron, 2010 , vol. 66, # 27-28 p. 5030 - 5035
反应条件
lithium hydroxide in tetrahydrofuran; water T=20°C;
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 20 p. 6074 - 6086
反应条件
1: aq. HCl / diethyl ether / 20 °C 2: CH2Cl2 / 20 °C 3: LiOH*H2O / tetrahydrofuran; H2O / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 20 p. 6074 - 6086
反应条件
1: CH2Cl2 / 20 °C 2: LiOH*H2O / tetrahydrofuran; H2O / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 20 p. 6074 - 6086
反应条件
1: CH2Cl2 / 20 °C 2: LiOH*H2O / tetrahydrofuran; H2O / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 20 p. 6074 - 6086
反应条件
sodium hydroxide 1.) H2O, 2.) H2O, tert-BuOH, 18 h;
参考文献
Biagini, Stefano C. G.; Gibson, Susan E.; Keen, Stephen P.
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 16 p. 2485 - 2499
反应条件
1: NaOH, H2O / ethanol / 16 h / Heating 2: HCl / H2O 3: 85 percent / NaOH, H2O / 20 h / Heating 4: 72 percent / NaOH / 1.) H2O, 2.) H2O, tert-BuOH, 18 h View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 16 p. 2485 - 2499
反应条件
1: 85 percent / NaOH, H2O / 20 h / Heating 2: 72 percent / NaOH / 1.) H2O, 2.) H2O, tert-BuOH, 18 h View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 16 p. 2485 - 2499
反应条件
boron trifluoride diethyl etherate in hexane; dichloromethane 19 h;
参考文献
Biagini, Stefano C. G.; Gibson, Susan E.; Keen, Stephen P.
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 16 p. 2485 - 2499
