6-氧代-1,6-二氢吡嗪-4-羧酸乙酯合成路线 （共 5 条）
反应条件
1: With sulfuric acid 5 h; Heating / reflux; 2: With water; sodium carbonate
参考文献
AstraZeneca AB
Patent: US2009/111822 A1, 2009 ;
Location in patent: Page/Page column 10 ;
US 20090111822 A1
反应条件
bromine; acetic acid
参考文献
McMillan; King
Journal of the American Chemical Society, 1955 , vol. 77, p. 3376
反应条件
1: water; N2H4 2: acetic acid; bromine View Scheme
参考文献
McMillan; King
Journal of the American Chemical Society, 1955 , vol. 77, p. 3376
反应条件
hydrogenchloride; water
参考文献
McMillan; King
Journal of the American Chemical Society, 1955 , vol. 77, p. 3376
参考文献
AstraZeneca AB
Patent: US2009/111822 A1, 2009 ;
Location in patent: Page/Page column 10 ;
US 20090111822 A1
