4-甲基-4'-硝基联苯合成路线 （共 71 条）
反应条件
caesium carbonate; [PdCl(NNCNHC-nBu)]BF4 in water; N,N-dimethyl-formamide
T=80°C; Suzuki-Miyaura reaction; 0.5 h;
参考文献
Zeng, Fanlong; Yu, Zhengkun
Journal of Organic Chemistry, 2006 , vol. 71, # 14 p. 5274 - 5281
反应条件
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); cesium fluoride in N,N-dimethyl-formamide
T=40°C; Stille reaction; 2 h;
参考文献
Mee, Simon P. H.; Lee, Victor; Baldwin, Jack E.
Chemistry - A European Journal, 2005 , vol. 11, # 11 p. 3294 - 3308
反应条件
palladium diacetate in water; N,N-dimethyl-formamide
T=20°C; 5 h;
参考文献
Yamamoto, Yasunori; Takizawa, Miho; Yu, Xiao-Qiang; Miyaura, Norio
Angewandte Chemie - International Edition, 2008 , vol. 47, # 5 p. 928 - 931
反应条件
2,2'-bis(di-p-tolyl-phosphino)-1,1'-binaphthyl; copper(I) oxide; 1,10-phenanthroline; palladium (II) bromide in 1-methyl-pyrrolidin-2-one
T=50 - 190°C; Microwave irradiationInert atmosphere;
参考文献
Goossen, Lukas J.; Linder, Christophe; Rodriguez, Nuria; Lange, Paul P.
Chemistry - A European Journal, 2009 , vol. 15, # 37 p. 9336 - 9349
反应条件
1,4-diaza-bicyclo[2.2.2]octane; tetrabutyl ammonium fluoride; palladium diacetate in 1,4-dioxane
T=80°C; Hiyama cross-coupling reaction; 4 h;
参考文献
Li, Jin-Heng; Deng, Chen-Liang; Liu, Wen-Jie; Xie, Ye-Xiang
Synthesis, 2005 , # 18 art. no. F08405SS, p. 3039 - 3044
反应条件
potassium phosphate; tetrakis(triphenylphosphine) palladium(0) in 1,4-dioxane
T=85°C; 2 h;
参考文献
Oh-e, Takayuki; Miyaura, Norio; Suzuki, Akira
Journal of Organic Chemistry, 1993 , vol. 58, # 8 p. 2201 - 2208
反应条件
copper(l) iodide; lithium chloride; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran; N,N-dimethyl-formamide
T=80°C; Stille coupling; 6 h;
参考文献
Hoshino, Masahide; Degenkolb, Peter; Curran, Dennis P.
Journal of Organic Chemistry, 1997 , vol. 62, # 24 p. 8341 - 8349
反应条件
copper(l) iodide; lithium chloride; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran; N,N-dimethyl-formamide
T=80°C; Stille coupling; 6 h;
参考文献
Hoshino, Masahide; Degenkolb, Peter; Curran, Dennis P.
Journal of Organic Chemistry, 1997 , vol. 62, # 24 p. 8341 - 8349
反应条件
potassium carbonate; polymer-supported Pd catalyst FC 1032 in ethanol
T=110°C; Suzuki coupling; 0.25 h; microwave irradiation;
参考文献
Wang, Ying; Sauer, Daryl R.
Organic Letters, 2004 , vol. 6, # 16 p. 2793 - 2796
反应条件
sodium carbonate; palladium on activated charcoal in ethanol; water
T=20°C; Suzuki-Miyaura cross-coupling; 1 h;
参考文献
Kitamura, Yoshiaki; Sakurai, Ai; Udzu, Takahiro; Maegawa, Tomohiro; Monguchi, Yasunari; Sajiki, Hironao
Tetrahedron, 2007 , vol. 63, # 43 p. 10596 - 10602
