(3S,4s)-4-(4-氯苯基)-1-甲基哌啶-3-羧酸甲酯合成路线 （共 2 条）
反应条件
1: 56 percent / diethyl ether / 0.5 h / -10 °C View Scheme
参考文献
Mobele, Bingidimi I.; Kinahan, Taryn; Ulysse, Luckner G.; Gagnier, Steven V.; Ironside, Michael D.; Knox, Graham S.; Mohammadi, Farahnaz
Organic Process Research and Development, 2006 , vol. 10, # 5 p. 914 - 920
反应条件
1: tert-butyl methyl ether; diethyl ether / 3 h / -20 - -5 °C / |Inert atmosphere 2: (2R,3S)-(-)-di-O-benzoyl tartaric acid / methanol / 0.5 h / 60 - 65 °C View Scheme
参考文献
Kozikowski, Alan P.; Araldi, Gian Luca; Boja, John; Meil, William M.; Johnson, Kenneth M.; Flippen-Anderson, Judith L.; George, Clifford; Saiah, Eddine
Journal of Medicinal Chemistry, 1998 , vol. 41, # 11 p. 1962 - 1969
