n-butyllithium in tetrahydrofuran; hexane T=-50 - 23°C; 4 h; Inert atmosphereFlow reactor;

1: tBuCH2CH2B(H)NiPr2; 4-fluorobenzenediazonium tetrafluoroborate With biscyclopentadienyliron(II) in acetonitrile T=20°C; 2.5 h; 2: With methanol in acetonitrile T=0 - 20°C; 1 h; 3: 2,3-dimethylbutane-2,3-diol in diethyl ether; acetonitrile T=20°C; 4 h; Reagent/catalyst;

potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in acetonitrile T=80°C; Microwave irradiation;

sodium sulfate in tetrahydrofuran T=20°C; 24 h; Schlenk techniqueInert atmosphere;

tert.-butylnitrite in acetonitrile T=80°C; 2 h;

boron trifluoride diethyl etherate in acetonitrile T=0 - 60°C; 1 h; Inert atmosphere;

in diethyl ether T=20°C; 4 h; Inert atmosphere;

1: With lithium bis((trifluoromethyl)sulfonyl)amide in tetrahydrofuran T=20°C; Electrochemical reaction; 2: With sulfuric acid T=0°C; pH=5; Further stages.;

1: Me2PhSiBpin With potassium methanolate in ethylene glycol dimethyl ether T=30°C; 0.166667 h; Inert atmosphere; 2: 1-bromo-4-fluorobenzene in ethylene glycol dimethyl ether T=30°C; 1 h;

1: 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl-4',4',5',5'-tetramethyl-1,3,2-dioxaborolane With dimethyl zinc; Mg(O-t-Bu)2 in 1,4-dioxane; hexane T=0 - 20°C; 0.5 h; Schlenk techniqueGloveboxInert atmosphere; 2: 1-bromo-4-fluoro-2-iodobenzene in 1,4-dioxane; hexane T=20 - 120°C; 24 h; Schlenk techniqueGloveboxInert atmosphere; 3: With water in 1,4-dioxane; hexane T=20°C; 0.0833333 h; Schlenk techniqueGloveboxInert atmosphere; Overall yield = 83 percent; regioselective reaction;