4-甲基-N-(1-甲基乙基)-苯甲酰胺合成路线 （共 10 条）
反应条件
4-methyl-morpholine in dichloromethane T=20°C; 2 h;
参考文献
Rolfe, Alan; Probst, Donald A.; Volp, Kelly A.; Omar, Iman; Flynn, Daniel L.; Hanson, Paul R.
Journal of Organic Chemistry, 2008 , vol. 73, # 22 p. 8785 - 8790
反应条件
pyridine in tetrahydrofuran T=20°C; 0.75 h;
参考文献
Rolfe, Alan; Probst, Donald A.; Volp, Kelly A.; Omar, Iman; Flynn, Daniel L.; Hanson, Paul R.
Journal of Organic Chemistry, 2008 , vol. 73, # 22 p. 8785 - 8790
反应条件
N,O-bis-(trimethylsilyl)-acetamide; PhCOSEt in chloroform-d1 T=20°C; 6 h;
参考文献
Wu, Wenting; Zhang, Zhihui; Liebeskind, Lanny S.
Journal of the American Chemical Society, 2011 , vol. 133, # 36 p. 14256 - 14259
反应条件
potassium hydroxide in dichloromethane; water T=22°C; 10 h;
参考文献
Al-Talib, Mahmoud; Jochims, Johannes C.
Chemische Berichte, 1985 , vol. 118, # 4 p. 1304 - 1314
反应条件
sodium in tetrahydrofuran Ambient temperatureultrasonic bath;
参考文献
Karaman, Rafik; Fry, James L.
Tetrahedron Letters, 1990 , vol. 31, # 7 p. 941 - 944
反应条件
1: 88 percent / triethylamine / CH2Cl2 / 1 h / Cooling 2: 18 percent Spectr. / tetrahydrofuran / 2 h / 20 °C View Scheme
参考文献
Przychodzen, Witold
Heteroatom Chemistry, 2006 , vol. 17, # 7 p. 676 - 684
反应条件
in tetrahydrofuran T=20°C; 2 h; Further byproducts given. Title compound not separated from byproducts;
参考文献
Przychodzen, Witold
Heteroatom Chemistry, 2006 , vol. 17, # 7 p. 676 - 684
反应条件
sodium hydroxide; potassium chloride; water T=100°C; hydrolysis and oxygen exchange rate constants; Rate constant;
参考文献
Journal of the American Chemical Society, , vol. 112, # 23 p. 8507 - 8514
反应条件
sodium hydroxide; potassium chloride; water T=100°C; hydrolysis and oxygen exchange rate constants; Rate constant;
参考文献
Slebocka-Tilk; Bennet; Keillor; Brown; Guthrie, J. Peter; Jodhan
Journal of the American Chemical Society, 1990 , vol. 112, # 23 p. 8507 - 8514
反应条件
TPPBr2; triethylamine in chloroform
T=-60°C; von Braun degradation; Reflux;
参考文献
Vaccari, Daniele; Davoli, Paolo; Spaggiari, Alberto; Prati, Fabio
Synlett, 2008 , # 9 p. 1317 - 1320
