4-氯-2-苯基噻吩并[3,2-d]嘧啶合成路线 （共 3 条）
反应条件
trichlorophosphate 4 h; Reflux;
参考文献
Snegaroff, Katia; Lassagne, Frederic; Bentabed-Ababsa, Ghenia; Nassar, Ekhlass; Ely, Sidaty Cheikh Sid; Stephanie Hesse; Perspicace, Enrico; Derdour, Aicha; Mongin, Florence
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 22 p. 4782 - 4788
反应条件
1: 1.) pyridine, 2.) 30percent NH3 / 1.) CHCl3, RT, overnight, 2.) 120 deg C, 2 h 2: 80 percent / POCl3 / 0.5 h / Heating View Scheme
参考文献
Crespo, Maria I.; Pages, Lluis; Vega, Armando; Segarra, Victor; Lopez, Manel; Domenech, Teresa; Miralpeix, Montserrat; Beleta, Jordi; Ryder, Hamish; Palacios, Jose M.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 21 p. 4021 - 4035
反应条件
1: 1.) pyridine, 2.) 30percent NH3 / 1.) CHCl3, RT, overnight, 2.) 120 deg C, 2 h 2: 80 percent / POCl3 / 0.5 h / Heating View Scheme
参考文献
Crespo, Maria I.; Pages, Lluis; Vega, Armando; Segarra, Victor; Lopez, Manel; Domenech, Teresa; Miralpeix, Montserrat; Beleta, Jordi; Ryder, Hamish; Palacios, Jose M.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 21 p. 4021 - 4035
