(S)-甲基 5-氧代四氢呋喃-2-羧酸合成路线 （共 13 条）
反应条件
1: With 9-methoxy-10,11-dihydrocinchonidine; hydrogen; 5percent Pt/Al2O3 in acetic acid T=20°C; Catalytic hydrogenation; P=750.075 Torr; 2: With toluene-4-sulfonic acid in acetic acid Cyclization; Further stages. Title compound not separated from byproducts.;
参考文献
Balazsik, Katalin; Szoeri, Kornel; Felfoeldi, Karoly; Toeroek, Bela; Bartok, Mihaly
Chemical Communications, 2000 , # 7 p. 555 - 556
反应条件
1: (S)-(+)-5-oxo-tetrahydrofuran-2-carboxylic acid With thionyl chloride 4 h; Heating; 2: methanol With triethylamine in dichloromethane T=20°C; 12 h; Further stages.;
参考文献
Huang, Pei-Qiang; Chen, Guo; Zheng, Xiao
Journal of Heterocyclic Chemistry, 2007 , vol. 44, # 2 p. 499 - 501
反应条件
Mucor rouxii freeze-dried yeast-like cells in hexane; water T=28°C; 24 h;
参考文献
Drioli, Sara; Nitti, Patrizia; Pitacco, Giuliana; Tossut, Laura; Valentin, Ennio
Tetrahedron Asymmetry, 1999 , vol. 10, # 14 p. 2713 - 2728
反应条件
1: Novozym 435 lipase B from Candida antarctica / 30 °C 2: Mucor rouxii freeze-dried yeast-like cells / hexane; H2O / 24 h / 28 °C View Scheme
参考文献
Drioli, Sara; Nitti, Patrizia; Pitacco, Giuliana; Tossut, Laura; Valentin, Ennio
Tetrahedron Asymmetry, 1999 , vol. 10, # 14 p. 2713 - 2728
参考文献
Pirc, Samo; Recnik, Simon; Skof, Marko; Svete, Jurij; Golic, Ljubo; Meden, Anton; Stanovnik, Branko
Journal of Heterocyclic Chemistry, 2002 , vol. 39, # 2 p. 411 - 416
反应条件
1: 82 percent / sodium nitrite in water / aq. HCl / 1.) 2 h, 5 deg C; 2.) r.t. 2: diethyl ether View Scheme
参考文献
Berti, Giancarlo; Caroti, Paola; Catelani, Giorgio; Monti, Luigi
Carbohydrate Research, 1983 , vol. 124, p. 35 - 42
反应条件
anhydrous magnesium perchlorate; 4R,9R-Me2PNPH in acetonitrile Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Ohno, Atsuyoshi; Yasuma, Tsuneo; Nakamura, Kaoru; Oka, Shinzaburo
Bulletin of the Chemical Society of Japan, 1986 , vol. 59, # 9 p. 2905 - 2906
反应条件
dicyclohexyl-carbodiimide in dichloromethane 1 h;
参考文献
Levy, Stuart G.; Jacques, Vincent; Zhou, Kevin Li; Kalogeropoulos, Shirley; Schumacher, Kelly; Amedio, John C.; Scherer, Jonathan E.; Witowski, Steven R.; Lombardy, Richard; Koppetsch, Karsten
Organic Process Research and Development, 2009 , vol. 13, # 3 p. 535 - 542
参考文献
Drioli, Sara; Nitti, Patrizia; Pitacco, Giuliana; Tossut, Laura; Valentin, Ennio
Tetrahedron Asymmetry, 1999 , vol. 10, # 14 p. 2713 - 2728
反应条件
hydrogenchloride 48 h; Ambient temperature;
参考文献
Berti, Giancarlo; Caroti, Paola; Catelani, Giorgio; Monti, Luigi
Carbohydrate Research, 1983 , vol. 124, p. 35 - 42
