2-氨基-6-氯苯甲酸合成路线

参考文献

Journal of Medicinal Chemistry, , vol. 36, # 4 p. 479 - 490

参考文献

Kondo, Kazumi; Ogawa, Hidenori; Yamashita, Hiroshi; Miyamoto, Hisashi; Tanaka, Michinori; Nakaya, Kenji; Kitano, Kazuyoshi; Yamamura, Yoshitaka; Nakamura, Shigeki; Onogawa, Toshiyuki; Mori, Toyoki; Tominaga, Michiaki
Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 8 p. 1743 - 1754

2148-56-32-氨基-6-氯苯甲酸

248282-10-25-氯-1,2-二氢-4-羟基-1-甲基-2-氧代-3-喹啉羧酸乙酯

参考文献

Joensson, Stig; Andersson, Gunnar; Fex, Tomas; Fristedt, Tomas; Hedlund, Gunnar; Jansson, Karl; Abramo, Lisbeth; Fritzson, Ingela; Pekarski, Olga; Runstroem, Anna; Sandin, Helena; Thuvesson, Ingela; Bjoerk, Anders
Journal of Medicinal Chemistry, 2004 , vol. 47, # 8 p. 2075 - 2088

2148-56-32-氨基-6-氯苯甲酸

269391-47-1+

616224-61-4Boc-2-氨基-6-氯苯甲酸

参考文献

Comess, Kenneth M.; Erickson, Scott A.; Henkin, Jack; Kalvin, Douglas M.; Kawai, Megumi; Kim, Ki H.; BaMaung, Nwe Y.; Park, Chang Hoon; Sheppard, George S.; Vasudevan, Anil; Wang, Jieyi; Barnes, David M.; Fidanze, Steve D.; Kolaczkowski, Lawrence; Mantei, Robert A.; Park, David C.; Sanders, William J.; Tedrow, Jason S.; Wang, Gary T.
Patent: US2004/157836 A1, 2004 ;

75-44-5光气+

2148-56-32-氨基-6-氯苯甲酸

20829-96-35-氯-3,1-苯并噁嗪-2,4-二酮

参考文献

Wennerberg, Johan; Bjoerk, Anders; Fristedt, Tomas; Granquis, Bo; Jansson, Karl; Thuvesson, Ingela
Organic Process Research and Development, 2007 , vol. 11, # 4 p. 674 - 680

32315-10-9三光气+

2148-56-32-氨基-6-氯苯甲酸

20829-96-35-氯-3,1-苯并噁嗪-2,4-二酮

参考文献

Tedesco, Rosanna; Shaw, Antony N.; Bambal, Ramesh; Chai, Deping; Concha, Nestor O.; Darcy, Michael G.; Dhanak, Dashyant; Fitch, Duke M.; Gates, Adam; Gerhardt, Warren G.; Halegoua, Dina L.; Han, Chao; Hofmann, Glenn A.; Johnston, Victor K.; Kaura, Arun C.; Liu, Nannan; Keenan, Richard M.; Lin-Goerke, Juili; Sarisky, Robert T.; Wiggall, Kenneth J.; Zimmerman, Michael N.; Duffy, Kevin J.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 3 p. 971 - 983

2148-56-32-氨基-6-氯苯甲酸+

75-36-5乙酰氯

20829-96-35-氯-3,1-苯并噁嗪-2,4-二酮

参考文献

ACTIVE BIOTECH AB
Patent: WO2003/106424 A1, 2003 ;
Location in patent: Page 5 ;

2148-56-32-氨基-6-氯苯甲酸

20829-96-35-氯-3,1-苯并噁嗪-2,4-二酮

参考文献

Wennerberg, Johan; Bjoerk, Anders; Fristedt, Tomas; Granquis, Bo; Jansson, Karl; Thuvesson, Ingela
Organic Process Research and Development, 2007 , vol. 11, # 4 p. 674 - 680

2148-56-32-氨基-6-氯苯甲酸

78754-81-15-氯喹唑啉-2,4(1H,3H)-二酮

参考文献

Snow, Roger John; Gao, Donghong A.; Goldberg, Daniel R.; Hammach, Abdelhakim; Kuzmich, Daniel; Morwick, Tina Marie; Moss, Neil; Prokopowicz III, Anthony S.; Selliah, Robert D.; Takahashi, Hidenori
Patent: US2002/119975 A1, 2002 ;
US 20020119975 A1

2148-56-32-氨基-6-氯苯甲酸+

57-13-6尿素

78754-81-15-氯喹唑啉-2,4(1H,3H)-二酮

参考文献

Van Horn, Kurt S.; Zhu, Xiaohua; Pandharkar, Trupti; Yang, Sihyung; Vesely, Brian; Vanaerschot, Manu; Dujardin, Jean-Claude; Rijal, Suman; Kyle, Dennis E.; Wang, Michael Zhuo; Werbovetz, Karl A.; Manetsch, Roman
Journal of Medicinal Chemistry, 2014 , vol. 57, # 12 p. 5141 - 5156