3,5-二甲氧基苯甲酸甲酯合成路线 （共 80 条）
反应条件
potassium carbonate in acetone 4 h;
参考文献
McNulty, James; McLeod, David
Tetrahedron Letters, 2013 , vol. 54, # 47 p. 6303 - 6306
反应条件
potassium carbonate in acetonitrile T=20°C;
参考文献
Song, Yu Min; Ha, Young Mi; Kim, Jin-Ah; Chung, Ki Wung; Uehara, Yohei; Lee, Kyung Jin; Chun, Pusoon; Byun, Youngjoo; Chung, Hae Young; Moon, Hyung Ryong
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 24 p. 7451 - 7455
反应条件
copper quinolate; tetra-(n-butyl)ammonium iodide in water; dimethyl sulfoxide T=120°C; 24 h;
参考文献
Zhu, Yan; Yan, Hong; Lu, Linhua; Liu, Defu; Rong, Guangwei; Mao, Jincheng
Journal of Organic Chemistry, 2013 , vol. 78, # 19 p. 9898 - 9905
反应条件
CuF2 in water; dimethyl sulfoxide T=120°C; 12 h; Schlenk techniqueInert atmosphereGreen chemistry;
参考文献
Li, Pan; Zhao, Jingjing; Lang, Rui; Xia, Chungu; Li, Fuwei
Tetrahedron Letters, 2014 , vol. 55, # 2 p. 390 - 393
参考文献
Shi, Feng; Shen, Jing Kang; Chen, Danqi; Fog, Karina; Thirstrup, Kenneth; Hentzer, Morten; Karlsson, Jens-Jakob; Menon, Veena; Jones, Kenneth A.; Smith, Kelli E.; Smith, Garrick
ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 4 p. 303 - 306
反应条件
potassium carbonate in acetone 10 h; Inert atmosphereReflux;
参考文献
Denmark, Scott E.; Kobayashi, Tetsuya; Regens, Christopher S.
Tetrahedron, 2010 , vol. 66, # 26 p. 4745 - 4759
反应条件
copper in N,N-dimethyl-formamide T=165°C; Ullmann coupling; 24 h;
参考文献
European Journal of Organic Chemistry, , # 6 p. 1096 - 1106
反应条件
sodium hydroxide in water T=80 - 90°C; pH=8.5 - 9; 2 h;
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 41, # 11 p. 2395 - 2398
反应条件
potassium phosphate; copper quinolate; tetra-(n-butyl)ammonium iodide in water; dimethyl sulfoxide T=120°C; 24 h;
参考文献
Zhu, Yan; Yan, Hong; Lu, Linhua; Liu, Defu; Rong, Guangwei; Mao, Jincheng
Journal of Organic Chemistry, 2013 , vol. 78, # 19 p. 9898 - 9905
反应条件
sulfuric acid; acetic acid T=85 - 90°C; 6 h; Neat (no solvent)Large scale reaction;
参考文献
Rekha; Ramani, Modukuri V.; Ratnamala; Rupakalpana, Vempati; Subbaraju, Gottumukkala V.; Satyanarayana, Chava; Rao, C. Someswara
Organic Process Research and Development, 2009 , vol. 13, # 4 p. 769 - 773
