3,5-二甲氧基苯甲酸甲酯合成路线 （共 80 条）
反应条件
(i) LiAlH4, (ii) MnO2; Multistep reaction;
参考文献
Takada, Akiomi; Hashimoto, Yoshimitsu; Takikawa, Hiroshi; Hikita, Katsuyoshi; Suzuki, Keisuke
Angewandte Chemie - International Edition, 2011 , vol. 50, # 10 p. 2297 - 2301
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran 2: With thionyl chloride in tetrahydrofuran; diethyl ether
参考文献
Jian, Yujuan; Sun, Gaojun; Li, Jiaming; Su, Dan; Li, Chuanrun; Zhong, Guochen
Chinese Journal of Chemistry, 2011 , vol. 29, # 7 p. 1423 - 1428
反应条件
sodium tetrahydroborate in methanol; ethylene glycol dimethyl ether 3 h; Heating;
参考文献
Jana, Nandan; Nanda, Samik
European Journal of Organic Chemistry, 2012 , # 23 p. 4313 - 4320
反应条件
trichlorophosphate T=0 - 20°C; Vilsmeier-Haack reaction; 4.5 h;
参考文献
Srivastava, Vandana; Darokar, Mahendra P.; Fatima, Atiya; Kumar; Chowdhury, Chinmay; Saxena, Hari Om; Dwivedi, Gaurav R.; Shrivastava, Kunal; Gupta, Vivek; Chattopadhyay; Luqman, Suaib; Gupta; Negi, Arvind S.; Khanuja, Suman P.S.
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 1 p. 518 - 525
反应条件
titanium tetrachloride Addition;
参考文献
Murty; Hazra; Datta; Mal
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1997 , vol. 36, # 2 p. 126 - 132
反应条件
LiSEt in N,N-dimethyl-formamide T=20°C; 19 h; Inert atmosphere;
参考文献
Cvengros, Jan; Neufeind, Stefan; Becker, Anne; Schmalz, Hans-Guenther
Synlett, 2008 , # 13 p. 1993 - 1998
反应条件
isopropylmagnesium chloride in tetrahydrofuran T=-10°C; 0.333333 h;
参考文献
Williams, J. Michael; Jobson, Ronald B.; Yasuda, Nobuyoshi; Marchesini, George; Dolling, Ulf-H.; Grabowski, Edward J. J.
Tetrahedron Letters, 1995 , vol. 36, # 31 p. 5461 - 5464
反应条件
1: liquid ammonia 2: aqueous sodium hypobromite / -15 °C View Scheme
参考文献
Monatshefte fuer Chemie, , vol. 57, p. 52,58
反应条件
1: 92.3 percent / LiAlH4 / diethyl ether / 4 h / Heating 2: 94.4 percent / SOCl2 / diethyl ether / 3 h / 20 °C 3: 4 h / Heating View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 53, # 12 p. 1587 - 1590
反应条件
1: LiAlH4 / diethyl ether 2: SOCl2 / diethyl ether 3: ethanol View Scheme
参考文献
Bhati,A.
Tetrahedron, 1962 , vol. 18, p. 1519 - 1526
