2,4-二甲氧基苯甲酸甲酯合成路线 （共 31 条）
参考文献
Van Otterlo, Willem A. L.; Michael, Joseph P.; De Koning, Charles B.
Synthetic Communications, 2007 , vol. 37, # 20 p. 3611 - 3621
反应条件
1: NaH 2: aqueous HCl; acetic acid View Scheme
参考文献
Kawase
Bulletin of the Chemical Society of Japan, 1958 , vol. 31, p. 390,392
反应条件
sodium methylate; 1,2-dichloro-benzene
参考文献
Long
Journal of the American Chemical Society, 1947 , vol. 69, p. 990,993
Full Text Show Details
Am. Cyanamid Co.
Patent: US2392167 , 1942 ;
反应条件
1: NaH 2: pyridine hydrochloride; hydrochloric acid View Scheme
参考文献
Kawase
Bulletin of the Chemical Society of Japan, 1959 , vol. 32, p. 690
反应条件
AlCl3, aluminium chloride in dichloromethane T=-5 - 25°C;
参考文献
Journal of Chemical Research, , # 4 p. 222 - 227
反应条件
3,3-dimethyldioxirane; tetra-(n-butyl)ammonium iodide in acetone T=25°C; regioselective reaction;
参考文献
Lee, Yean-Jang; Wu, Huan-Ting; Lin, Chia-Ning
Letters in Organic Chemistry, 2009 , vol. 6, # 7 p. 585 - 587
反应条件
1: 1-bromo-2,4-dimethoxy-benzene With n-butyllithium in diethyl ether; hexane
0.166667 h; Inert atmosphereCooling with ice;
2: methyl 2,4-dimethoxy-benzoate in diethyl ether; hexane
0.05 h;
参考文献
Indicator Systems International, Inc.; Gorski, Joel R.; Booher, Jon; Sabnis, Ram W.
Patent: US8425996 B2, 2013 ;
Location in patent: Page/Page column 19; 20 ;
参考文献
Kauffmann; Kieser
Chemische Berichte, 1912 , vol. 45, p. 2334
Chemische Berichte, 1913 , vol. 46, p. 3801 Anm. 1
反应条件
in diethyl ether; benzene
2 h; Heating;
参考文献
MacKnight, Earl; McClelland, Robert A.
Canadian Journal of Chemistry, 1996 , vol. 74, # 12 p. 2518 - 2527
反应条件
1: sodium ethylate; benzene
2: HCl
3: concentrated aqueous HCl; acetic acid
View Scheme
参考文献
Kawase
Bulletin of the Chemical Society of Japan, 1958 , vol. 31, p. 390,392
