3,5-二羟基苯甲酸甲酯合成路线 （共 124 条）
反应条件
1: imidazole / dimethylformamide 2: LiAlH4 / tetrahydrofuran / 0 °C View Scheme
参考文献
L'abbe, Gerrit; Forier, Bart; Dehaen, Wim
Chemical Communications, 1996 , # 18 p. 2143 - 2144
反应条件
1: 94 percent / imidazole / dimethylformamide / 24 h / Ambient temperature 2: 95 percent / lithium aluminium hydride / diethyl ether / 1.) 30 min 2.) reflux, 1 h 3: 86 percent / Ph3P / CCl4 / 2 h / 75 - 80 °C 4: 83 percent / xylene / 10 h / Heating 5: 1.) n-BuLi / 1.) benzene, 30 min 2.) benzene, 4 h 6: 40percent aq. HF / acetonitrile / 4 h / Ambient temperature View Scheme
参考文献
Cardona, Luz; Fernandez, Isabel; Garcia, Begona; Pedro, Jose R.
Tetrahedron, 1986 , vol. 42, # 10 p. 2725 - 2730
反应条件
potassium carbonate in acetonitrile T=20°C;
参考文献
Song, Yu Min; Ha, Young Mi; Kim, Jin-Ah; Chung, Ki Wung; Uehara, Yohei; Lee, Kyung Jin; Chun, Pusoon; Byun, Youngjoo; Chung, Hae Young; Moon, Hyung Ryong
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 24 p. 7451 - 7455
反应条件
potassium carbonate in acetone 10 h; Inert atmosphereReflux;
参考文献
Denmark, Scott E.; Kobayashi, Tetsuya; Regens, Christopher S.
Tetrahedron, 2010 , vol. 66, # 26 p. 4745 - 4759
反应条件
potassium carbonate in acetone 18 h; Heating;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1467 - 1476
反应条件
potassium carbonate in butanone Heating;
参考文献
Donnio, Bertrand; Bruce, Duncan W.
Journal of the Chemical Society - Dalton Transactions, 1997 , # 16 p. 2745 - 2755
反应条件
1.1: K2CO3 / dimethylformamide / 2 h / 20 °C 1.2: 96 percent / dimethylformamide / 14.5 h / 20 °C 2.1: 95 percent / LiAlH4 / diethyl ether / 4 h / 20 °C View Scheme
参考文献
Denmark, Scott E.; Regens, Christopher S.; Kobayashi, Tetsuya
Journal of the American Chemical Society, 2007 , vol. 129, # 10 p. 2774 - 2776
反应条件
1: 65 percent / K2CO3 / 18-crown-6 / acetone 2: 86 percent / LiAlH4 / diethyl ether 3: 98 percent / triton B / 18 h / 20 °C 4: 69 percent / pyridine / 6 h / Heating 5: 30 percent / cc. HCl / methanol / 6 h / Heating 6: 13 percent / toluene-p-sulphonic acid / CH2Cl2 / 2.75 h / Heating View Scheme
参考文献
Crombie, Leslie; Crombie, W. Mary L.; Tuchinda, Patoomratana
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 1255 - 1262
反应条件
1: 98 percent / K2CO3 / dimethylformamide / 24 h / 80 °C 2: 97 percent / KOH / methanol; H2O / 12 h / 60 °C View Scheme
参考文献
Ziessel, Raymond; Pickaert, Guillaume; Camerel, Franck; Donnio, Bertrand; Guillon, Daniel; Cesario, Michele; Prange, Thierry
Journal of the American Chemical Society, 2004 , vol. 126, # 39 p. 12403 - 12413
反应条件
potassium carbonate in N,N-dimethyl-formamide T=60°C;
参考文献
Iino, Tomoharu; Tsukahara, Daisuke; Kamata, Kenji; Sasaki, Kaori; Ohyama, Sumika; Hosaka, Hideka; Hasegawa, Takuro; Chiba, Masato; Nagata, Yasufumi; Eiki, Jun-ichi; Nishimura, Teruyuki
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 7 p. 2733 - 2743
