2,5-二羟基苯甲酸甲酯合成路线 （共 43 条）
反应条件
hydrogenchloride in methanol 8 h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 51, # 4 p. 508 - 512
反应条件
aluminium trichloride; 1-octadecanol in toluene Ambient temperature;
参考文献
Tetrahedron, , vol. 54, # 9 p. 1943 - 1952
参考文献
Justus Liebigs Annalen der Chemie, , vol. 340, p. 219
参考文献
Justus Liebigs Annalen der Chemie, , vol. 340, p. 219
反应条件
potassium carbonate in acetone 6 h; Heating;
参考文献
Mondal, Mukulesh; Puranik, Vedavati G.; Argade, Narshinha P.
Journal of Organic Chemistry, 2006 , vol. 71, # 13 p. 4992 - 4995
反应条件
1: potassium carbonate / acetonitrile / 20 °C 2: sodium hydroxide / 1,4-dioxane / 5 h / 20 °C 3: triethylamine; diphenyl phosphoryl azide / 80 °C View Scheme
参考文献
Song, Yu Min; Ha, Young Mi; Kim, Jin-Ah; Chung, Ki Wung; Uehara, Yohei; Lee, Kyung Jin; Chun, Pusoon; Byun, Youngjoo; Chung, Hae Young; Moon, Hyung Ryong
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 24 p. 7451 - 7455
反应条件
1: 70 percent / K2CO3 / acetone / 10 h 2: 87 percent / KF / dimethylformamide / 1 h / 100 - 110 °C 3: 1.) aq. Na2S2O4, 2.) conc. H2SO4 / 1.) CH2Cl2, 2.) 5 min (room temperature), 15 - 20 min, 60 deg C 4: 79 percent / K2CO3 / acetone / 0.75 h View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 7 p. 1507 - 1510
反应条件
1: potassium carbonate / acetonitrile / 20 °C 2: sodium hydroxide / 1,4-dioxane / 5 h / 20 °C View Scheme
参考文献
Song, Yu Min; Ha, Young Mi; Kim, Jin-Ah; Chung, Ki Wung; Uehara, Yohei; Lee, Kyung Jin; Chun, Pusoon; Byun, Youngjoo; Chung, Hae Young; Moon, Hyung Ryong
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 24 p. 7451 - 7455
反应条件
1: 2,5-dihydroxybenzoic acid methyl ester With pyridine in dichloromethane T=-78°C; 0.166667 h; Inert atmosphere; 2: trifluoromethylsulfonic anhydride in dichloromethane T=-78 - 0°C; 4 h; Inert atmosphere;
参考文献
Nawaz, Muhammad; Ullah, Ihsan; Abid, Obaid-Ur-Rahman; Ali, Asad; Patonay, Tamas; Saghyan, Ashot S.; Ghochikan, Tariel V.; Villinger, Alexander; Langer, Peter
Canadian Journal of Chemistry, 2013 , vol. 91, # 11 p. 1048 - 1058
反应条件
potassium carbonate in acetone 48 h; Reflux; chemoselective reaction;
参考文献
Yan, Yan; Qin, Bo; Ren, Changliang; Yip, Yeow Kwan; Ye, Ruijuan; Zeng, Huaqiang; Chen, Xiuying; Su, Haibin; Zhang, Dawei
Journal of the American Chemical Society, 2010 , vol. 132, # 16 p. 5869 - 5879
