hydrogen; PtO2/C in ethanol 1 h;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11460447', constants.ctx, '0')">lithium aluminium tetrahydride</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1696894', constants.ctx, '0')">diethyl ether</a> <br />T=0&deg;C;&nbsp;1&nbsp;h;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 5 steps<br /> </b>1: 5 mg / DIPEA / CH₂Cl₂ / 3 h / Ambient temperature<br />2: 88 percent / K₂CO₃ / methanol; tetrahydrofuran / 0.5 h<br />3: 90 percent / aq. HCl / methanol / 3 h<br />4: 89 percent / K₂CO₃ / acetone / 1 h<br />5: 84 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 1 h / 0 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 88 percent / K₂CO₃ / methanol; tetrahydrofuran / 0.5 h<br />2: 90 percent / aq. HCl / methanol / 3 h<br />3: 89 percent / K₂CO₃ / acetone / 1 h<br />4: 84 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 1 h / 0 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 90 percent / aq. HCl / methanol / 3 h<br />2: 89 percent / K₂CO₃ / acetone / 1 h<br />3: 84 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 1 h / 0 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 88 percent / K₂CO₃ / methanol / 0.5 h<br />2: 89 percent / K₂CO₃ / acetone / 1 h<br />3: 84 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 1 h / 0 &deg;C<br /> <br /> &nbsp;