1: 4-carboxybenzenesulfonyl chloride With sodium hydrogencarbonate; sodium sulfite in water
T=75°C; 1.33333 h;
2: 2-chloro-propionic acid With sodium hydroxide in water
T=105°C; 72 h;
参考文献
Wyeth
Patent: US2006/19965 A1, 2006 ;
Location in patent: Page/Page column 77 ;
US 20060019965 A1