反应条件
1: 1-ethyl-1H-1,2,4-triazole With n-butyllithium in tetrahydrofuran; hexane T=-40°C; 2: N,N-dimethyl-formamide in tetrahydrofuran; hexane T=-40 - 20°C; 2.25 h; 3: With sodium tetrahydroborate in tetrahydrofuran; methanol; hexane T=20°C; 14 h;
参考文献
Carling, Robert W.; Madin, Andrew; Guiblin, Alec; Russell, Michael G. N.; Moore, Kevin W.; Mitchinson, Andrew; Sohal, Bindi; Pike, Andrew; Cook, Susan M.; Ragan, Ian C.; McKernan, Ruth M.; Quirk, Kathleen; Ferris, Pushpinder; Marshall, George; Thompson, Sally Ann; Wafford, Keith A.; Dawson, Gerard R.; Atack, John R.; Harrison, Timothy; Castro, Jose L.; Street, Leslie J.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 23 p. 7089 - 7092
