3-(4-哌啶)1,3-苯并恶唑-2-(3H)酮合成路线 （共 6 条）
反应条件
hydrogenchloride Yield given;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 18 p. 2467 - 2472
反应条件
1: With pyridine in tetrahydrofuran 2: With trifluoroacetic acid in dichloromethane T=0 - 20°C;
参考文献
WO2011/143444 A2, ;
Page/Page column 7; 87-90 ;
反应条件
1: NaBH(OAc)3 / 1,2-dichloro-ethane / 20 °C 2: pyridine / tetrahydrofuran / 60 °C 3: conc. HCl / 50 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 12 p. 3421 - 3425
反应条件
1: NaBH(OAc)3 / 1,2-dichloro-ethane / 20 °C 2: pyridine / tetrahydrofuran / 60 °C 3: conc. HCl / 50 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 12 p. 3421 - 3425
反应条件
1: pyridine / tetrahydrofuran / 60 °C 2: conc. HCl / 50 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 12 p. 3421 - 3425
反应条件
1.1: sodium tris(acetoxy)borohydride / 1,2-dichloro-ethane / 20 °C 2.1: pyridine / tetrahydrofuran 2.2: 0 - 20 °C View Scheme
