甲基3-氨基-2-萘甲酸酯合成路线 （共 20 条）
反应条件
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine in dichloromethane T=20°C; 12 h;
参考文献
KIRIN BEER KABUSHIKI KAISHA
Patent: EP1614676 A1, 2006 ;
Location in patent: Page/Page column 185 ;
EP 1614676 A1
反应条件
in tetrahydrofuran; methanol T=20°C; 24 h;
参考文献
Pardo, Carmen; Pirat, Celine; Elguero, Jose
Journal of Heterocyclic Chemistry, 2007 , vol. 44, # 6 p. 1303 - 1307
反应条件
4-(N,N-dimethlyamino)pyridine in DMF (N,N-dimethyl-formamide) 16 h;
参考文献
Allison, Brett; McAtee, Laura C.; Phuong, Victor K.; Rabinowitz, Michael H.; Shankley, Nigel P.
Patent: US2004/224983 A1, 2004 ;
Location in patent: Page 26-27 ;
反应条件
sulfuric acid Heating;
参考文献
Taffarel, Emmanuelle; Chirayil, Sarah; Thummel, Randolph P.
Journal of Organic Chemistry, 1994 , vol. 59, # 4 p. 823 - 828
反应条件
hydrogenchloride T=20°C; 12 h;
参考文献
Theeraladanon, Chumpol; Arisawa, Mitsuhiro; Nishida, Atsushi; Nakagawa, Masako
Tetrahedron, 2004 , vol. 60, # 13 p. 3017 - 3035
反应条件
in diethyl ether 1 h; Inert atmosphere;
参考文献
Levesque, Patrick; Fournier, Pierre-Andre
Journal of Organic Chemistry, 2010 , vol. 75, # 20 p. 7033 - 7036
反应条件
1: 52 percent / 30percent aq. NH3, ZnCl2 / 36 h / 195 °C 2: 60 percent / conc. H2SO4 / Heating View Scheme
参考文献
Taffarel, Emmanuelle; Chirayil, Sarah; Thummel, Randolph P.
Journal of Organic Chemistry, 1994 , vol. 59, # 4 p. 823 - 828
参考文献
Gen. Aniline Works
Patent: US1903880 , 1929 ;
Full Text Show Details
I.G. Farbenind.
Patent: DE514596 , 1928 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 17, p. 698,700
反应条件
1.) pyrolysis 850 deg C/0.001 Torr,; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Wentrup, Curt; Bender, Harald; Gross, Gerhard
Journal of Organic Chemistry, 1987 , vol. 52, # 17 p. 3838 - 3847
反应条件
tert-butylamine in methanol 48 h; Ambient temperature; Further byproducts given;
参考文献
Journal of Organic Chemistry, , vol. 59, # 8 p. 2156 - 2163
