N-(4-氯苯基)-beta-丙氨酸合成路线 （共 8 条）
反应条件
sodium hydroxide; sodium chloride in water
参考文献
Mochida Pharmaceutical Co., Ltd.
Patent: US6018046 A1, 2000 ;
反应条件
sodium hydroxide; water 4 h; Heating / reflux;
参考文献
Konradi, Andrei W.; Probst, Gary; Aubele, Danielle L.; Garofalo, Albert W.; Hom, Roy; Neitzel, Martin L.; Semko, Christopher M.; Truong, Anh P.
Patent: US2008/21056 A1, 2008 ;
Location in patent: Page/Page column 78; 79 ;
US 20080021056 A1
参考文献
Elderfield; Maggiolo
Journal of the American Chemical Society, 1949 , vol. 71, p. 1906,1910
反应条件
1: acetic acid 2: aqueous NaOH-solution View Scheme
参考文献
Elderfield; Maggiolo
Journal of the American Chemical Society, 1949 , vol. 71, p. 1906,1910
参考文献
Hurd; Hayao
Journal of the American Chemical Society, 1952 , vol. 74, p. 5889,5891
反应条件
T=326.84°C; 0.25 h; Kinetics; Further Variations:Temperatures;
参考文献
Tetrahedron, , vol. 60, # 13 p. 3045 - 3049
反应条件
T=326.84°C; 0.25 h; Kinetics; Further Variations:Temperatures;
参考文献
Al-Awadi, Sundus A.; Abdallah, Mariam R.; Hasan, Mohamad A.; Al-Awadi, Nouria A.
Tetrahedron, 2004 , vol. 60, # 13 p. 3045 - 3049
反应条件
1: benzene; pyridine
2: phosphoryl chloride / 100 °C / Erhitzen des Reaktionsprodukts mit einem Gemisch von Essigsaeure und konz.wss.Salzsaeure.
View Scheme
参考文献
Elderfield; Maggiolo
Journal of the American Chemical Society, 1949 , vol. 71, p. 1906,1910
