1: 83 percent / mercury(II) chloride; calcium carbonate / H2O; acetonitrile / 1 h / 20 °C 2: 85 percent / aq. NaOH / methanol / 3 h / Heating View Scheme

<b>Multi-step reaction with 4 steps<br /> </b>1.1: sodium hydride / tetrahydrofuran / 1 h / 20 &deg;C<br />2.1: 317 mg / zinc borohydride / diethyl ether / 0.5 h / 0 &deg;C<br />3.1: 87 percent / mesyl chloride; N,N-diisopropylethylamine / CH₂Cl₂ / 0.83 h / 0 - 20 &deg;C<br />4.1: methylmagnesium iodide / diethyl ether; tetrahydrofuran / 1 h / -10 - 20 &deg;C<br />4.2: 50 percent / diethyl ether; tetrahydrofuran / 2 h / -10 - 20 &deg;C<br /> <br /> &nbsp;